"B7-1 Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A costimulatory ligand membrane glycoprotein that contains a V2 type and C2 IMMUNOGLOBULIN DOMAIN and is expressed by ANTIGEN-PRESENTING CELLS. It binds to CTLA-4 ANTIGEN with high specificity and to CD28 ANTIGEN with low specificity. The interaction of CD80 with CD28 ANTIGEN provides a costimulatory signal to T-LYMPHOCYTES, while its interaction with CTLA-4 ANTIGEN may play a role in inducing PERIPHERAL TOLERANCE.
| Descriptor ID |
D018122
|
| MeSH Number(s) |
D12.776.467.150.100 D12.776.543.095.100 D23.050.301.285.100 D23.529.168.100
|
| Concept/Terms |
B7-1 Antigen- B7-1 Antigen
- B7 1 Antigen
- CD80 Antigen
- CD80 Antigens
- B7-1 Ligand
- B7 1 Ligand
- Ligand, B7-1
- B7-1 Costimulatory Molecule
- B7 1 Costimulatory Molecule
- Costimulatory Molecule, B7-1
- Antigen, B7-1
- Antigen, B7 1
- B-Cell Activation Antigen
- B Cell Activation Antigen
- Antigens, CD80
|
Below are MeSH descriptors whose meaning is more general than "B7-1 Antigen".
Below are MeSH descriptors whose meaning is more specific than "B7-1 Antigen".
This graph shows the total number of publications written about "B7-1 Antigen" by people in this website by year, and whether "B7-1 Antigen" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 4 | 1 | 5 |
| 1996 | 4 | 1 | 5 |
| 1997 | 3 | 1 | 4 |
| 1998 | 4 | 0 | 4 |
| 1999 | 2 | 2 | 4 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 5 | 7 |
| 2002 | 2 | 0 | 2 |
| 2003 | 3 | 3 | 6 |
| 2004 | 4 | 2 | 6 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 2 | 3 | 5 |
| 2013 | 0 | 4 | 4 |
| 2016 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "B7-1 Antigen" by people in Profiles.
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CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment. Immunity. 2024 May 14; 57(5):1071-1086.e7.
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Dendritic Cells Coordinate the Development and Homeostasis of Organ-Specific Regulatory T Cells. Immunity. 2016 Apr 19; 44(4):847-59.
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Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4? T cells. Immunity. 2013 Sep 19; 39(3):560-72.
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The use of self-adjuvanting nanofiber vaccines to elicit high-affinity B cell responses to peptide antigens without inflammation. Biomaterials. 2013 Nov; 34(34):8776-85.
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Human hepatic stellate cells inhibit T-cell response through B7-H1 pathway. Transplantation. 2013 Jul 15; 96(1):17-24.
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Transplantation: The promise of co-stimulatory blockade in transplantation. Nat Rev Nephrol. 2013 Apr; 9(4):189-90.
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Lactobacilli secreting a tumor antigen and IL15 activates neutrophils and dendritic cells and generates cytotoxic T lymphocytes against cancer cells. Cell Immunol. 2011; 271(1):89-96.
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B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis. Eur J Immunol. 2010 Nov; 40(11):3117-27.
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Immunoglobulin-like transcript 3, an inhibitor of T cell activation, is reduced on blood monocytes during multiple sclerosis relapses and is induced by interferon beta-1b. Mult Scler. 2010 Jan; 16(1):30-8.
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Mechanistic insights into immunomodulation by hepatic stellate cells in mice: a critical role of interferon-gamma signaling. Hepatology. 2009 Dec; 50(6):1981-91.