"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 10 | 14 |
| 1997 | 2 | 9 | 11 |
| 1998 | 6 | 7 | 13 |
| 1999 | 7 | 14 | 21 |
| 2000 | 4 | 5 | 9 |
| 2001 | 5 | 17 | 22 |
| 2002 | 7 | 19 | 26 |
| 2003 | 6 | 12 | 18 |
| 2004 | 7 | 18 | 25 |
| 2005 | 5 | 14 | 19 |
| 2006 | 4 | 12 | 16 |
| 2007 | 1 | 18 | 19 |
| 2008 | 7 | 8 | 15 |
| 2009 | 7 | 19 | 26 |
| 2010 | 5 | 11 | 16 |
| 2011 | 4 | 11 | 15 |
| 2012 | 7 | 8 | 15 |
| 2013 | 5 | 22 | 27 |
| 2014 | 2 | 15 | 17 |
| 2015 | 4 | 15 | 19 |
| 2016 | 8 | 20 | 28 |
| 2017 | 5 | 12 | 17 |
| 2018 | 4 | 13 | 17 |
| 2019 | 5 | 8 | 13 |
| 2020 | 4 | 12 | 16 |
| 2021 | 8 | 13 | 21 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 3 | 3 |
| 2024 | 3 | 7 | 10 |
| 2025 | 1 | 6 | 7 |
| 2026 | 0 | 3 | 3 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Post-COVID impairment of T cell responses to community-acquired pathogens can be modified by activating cellular metabolism. PLoS Pathog. 2026 07; 22(7):e1013860.
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TCR? constant usage tunes human ?d T cell antigen sensitivity, thymic programming, and peripheral function. Sci Immunol. 2026 Feb 13; 11(116):eadr7167.
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Transcription factor Etv3 controls the tolerogenic function of dendritic cells. Science. 2026 Feb 12; 391(6786):eads1246.
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Radiotherapy induces YTHDF2 in dendritic cells impairing cross-presentation and T cell function. J Exp Med. 2026 01 05; 223(1).
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NNMT inhibition in cancer-associated fibroblasts restores antitumour immunity. Nature. 2025 09; 645(8082):1051-1059.
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Treg activation during allograft tolerance induction requires mitochondrion-induced TGF-ß1 in type 1 conventional dendritic cells. J Clin Invest. 2025 09 16; 135(18).
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Disruption of riboflavin biosynthesis in mycobacteria establishes riboflavin pathway intermediates as key precursors of MAIT cell agonists. PLoS Pathog. 2025 07; 21(7):e1012632.
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Dendritic cell-derived exosomes induce monocyte antigen-presentation and immune amplification in neoantigen vaccine therapy. Front Immunol. 2025; 16:1565696.
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Deconvoluting TCR-dependent and -independent activation is vital for reliable Ag-specific CD4+ T cell characterization by AIM assay. Sci Adv. 2025 Apr 25; 11(17):eadv3491.
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Mapping the extracellular molecular architecture of the pAg-signaling complex with a-Butyrophilin antibodies. Sci Rep. 2025 Apr 09; 15(1):12162.