"Lymphocyte Activation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Morphologic alteration of small B LYMPHOCYTES or T LYMPHOCYTES in culture into large blast-like cells able to synthesize DNA and RNA and to divide mitotically. It is induced by INTERLEUKINS; MITOGENS such as PHYTOHEMAGGLUTININS, and by specific ANTIGENS. It may also occur in vivo as in GRAFT REJECTION.
| Descriptor ID |
D008213
|
| MeSH Number(s) |
E01.370.225.812.482 E05.200.812.482 E05.478.594.530 G12.450.050.400.545 G12.565
|
| Concept/Terms |
Lymphocyte Activation- Lymphocyte Activation
- Activation, Lymphocyte
- Blast Transformation
- Blastogenesis
- Lymphocyte Stimulation
- Stimulation, Lymphocyte
- Lymphocyte Transformation
- Transformation, Lymphoblast
- Lymphoblast Transformation
- Transformation, Blast
- Transformation, Lymphocyte
|
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Activation".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Activation".
This graph shows the total number of publications written about "Lymphocyte Activation" by people in this website by year, and whether "Lymphocyte Activation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 4 | 12 | 16 |
| 1996 | 4 | 9 | 13 |
| 1997 | 2 | 9 | 11 |
| 1998 | 6 | 7 | 13 |
| 1999 | 7 | 15 | 22 |
| 2000 | 4 | 5 | 9 |
| 2001 | 5 | 17 | 22 |
| 2002 | 7 | 20 | 27 |
| 2003 | 6 | 12 | 18 |
| 2004 | 7 | 18 | 25 |
| 2005 | 5 | 14 | 19 |
| 2006 | 5 | 12 | 17 |
| 2007 | 2 | 17 | 19 |
| 2008 | 7 | 8 | 15 |
| 2009 | 7 | 18 | 25 |
| 2010 | 5 | 10 | 15 |
| 2011 | 3 | 11 | 14 |
| 2012 | 7 | 8 | 15 |
| 2013 | 5 | 20 | 25 |
| 2014 | 2 | 15 | 17 |
| 2015 | 4 | 14 | 18 |
| 2016 | 6 | 18 | 24 |
| 2017 | 5 | 12 | 17 |
| 2018 | 4 | 12 | 16 |
| 2019 | 4 | 8 | 12 |
| 2020 | 4 | 7 | 11 |
| 2021 | 7 | 13 | 20 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 3 | 3 |
| 2024 | 3 | 7 | 10 |
| 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Lymphocyte Activation" by people in Profiles.
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Dendritic cell-derived exosomes induce monocyte antigen-presentation and immune amplification in neoantigen vaccine therapy. Front Immunol. 2025; 16:1565696.
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Mapping the extracellular molecular architecture of the pAg-signaling complex with a-Butyrophilin antibodies. Sci Rep. 2025 Apr 09; 15(1):12162.
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Central control of dynamic gene circuits governs T cell rest and activation. Nature. 2025 Jan; 637(8047):930-939.
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NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs. Cancer Immunol Res. 2024 Oct 01; 12(10):1421-1437.
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Ligand-induced segregation from large cell-surface phosphatases is a critical step in ?d TCR triggering. Cell Rep. 2024 09 24; 43(9):114761.
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Androgens contribute to sex bias of autoimmunity in mice by T cell-intrinsic regulation of Ptpn22 phosphatase expression. Nat Commun. 2024 Sep 03; 15(1):7688.
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Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells. J Leukoc Biol. 2024 Jun 28; 116(1):6-17.
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Obesity induces PD-1 on macrophages to suppress anti-tumour immunity. Nature. 2024 Jun; 630(8018):968-975.
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Cancer Cell Small Molecule Secretome Induces the Immune Checkpoint NKG2A and Dysfunction of Human CD8+ T Cells. Immunohorizons. 2024 06 01; 8(6):464-477.
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Immunotherapy-activated T cells recruit and skew late-stage activated M1-like macrophages that are critical for therapeutic efficacy. Cancer Cell. 2024 Jun 10; 42(6):1032-1050.e10.