"Podocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Highly differentiated epithelial cells of the visceral layer of BOWMAN CAPSULE of the KIDNEY. They are composed of a cell body with major CELL SURFACE EXTENSIONS and secondary fingerlike extensions called pedicels. They enwrap the KIDNEY GLOMERULUS capillaries with their cell surface extensions forming a filtration structure. The pedicels of neighboring podocytes interdigitate with each other leaving between them filtration slits that are bridged by an extracellular structure impermeable to large macromolecules called the slit diaphragm, and provide the last barrier to protein loss in the KIDNEY.
| Descriptor ID |
D050199
|
| MeSH Number(s) |
A05.810.453.324.359.372.650 A05.810.453.736.520.720 A11.436.720
|
| Concept/Terms |
Podocytes- Podocytes
- Podocyte
- Glomerular Visceral Epithelial Cells
- Visceral Epithelial Cells, Glomerular
- Epithelial Cells, Glomerular Visceral
|
Below are MeSH descriptors whose meaning is more general than "Podocytes".
Below are MeSH descriptors whose meaning is more specific than "Podocytes".
This graph shows the total number of publications written about "Podocytes" by people in this website by year, and whether "Podocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 1 | 3 |
| 2009 | 0 | 3 | 3 |
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 1 | 3 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 1 | 0 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Podocytes" by people in Profiles.
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Podocyte injury at young age causes premature senescence and worsens glomerular aging. Am J Physiol Renal Physiol. 2024 01 01; 326(1):F120-F134.
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Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span. Aging (Albany NY). 2023 07 23; 15(14):6658-6689.
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Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease. J Clin Invest. 2022 08 15; 132(16).
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Deiodinase-3 is a thyrostat to regulate podocyte homeostasis. EBioMedicine. 2021 Oct; 72:103617.
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Differential expression of parietal epithelial cell and podocyte extracellular matrix proteins in focal segmental glomerulosclerosis and diabetic nephropathy. Am J Physiol Renal Physiol. 2019 12 01; 317(6):F1680-F1694.
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A novel acetyltransferase p300 inhibitor ameliorates hypertension-associated cardio-renal fibrosis. Epigenetics. 2017; 12(11):1004-1013.
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WT1 Is Necessary for the Proliferation and Migration of Cells of Renin Lineage Following Kidney Podocyte Depletion. Stem Cell Reports. 2017 10 10; 9(4):1152-1166.
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Loss of the podocyte-expressed transcription factor Tcf21/Pod1 results in podocyte differentiation defects and FSGS. J Am Soc Nephrol. 2014 Nov; 25(11):2459-70.
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Vitamin D receptor signaling in renal and cardiovascular protection. Semin Nephrol. 2013 Sep; 33(5):433-47.
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Vitamin D in chronic kidney disease. Contrib Nephrol. 2013; 180:98-109.