"Paneth Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Differentiated epithelial cells of the INTESTINAL MUCOSA, found in the basal part of the intestinal crypts of Lieberkuhn. Paneth cells secrete GROWTH FACTORS, digestive enzymes such as LYSOZYME and antimicrobial peptides such as cryptdins (ALPHA-DEFENSINS) into the crypt lumen.
| Descriptor ID |
D019879
|
| MeSH Number(s) |
A03.556.124.369.700 A10.615.550.444.700 A11.436.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Paneth Cells".
Below are MeSH descriptors whose meaning is more specific than "Paneth Cells".
This graph shows the total number of publications written about "Paneth Cells" by people in this website by year, and whether "Paneth Cells" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Paneth Cells" by people in Profiles.
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Peptide YY: A Paneth cell antimicrobial peptide that maintains Candida gut commensalism. Science. 2023 08 04; 381(6657):502-508.
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Regulation of the Paneth cell niche by exogenous L-arginine couples the intestinal stem cell function. FASEB J. 2020 08; 34(8):10299-10315.
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A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease. Eur J Gastroenterol Hepatol. 2018 08; 30(8):828-837.
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Vitamin D receptor pathway is required for probiotic protection in colitis. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 01; 309(5):G341-9.
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Bombesin Preserves Goblet Cell Resistin-Like Molecule ß During Parenteral Nutrition but Not Other Goblet Cell Products. JPEN J Parenter Enteral Nutr. 2016 09; 40(7):1042-9.
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Pathogenesis of necrotizing enterocolitis: modeling the innate immune response. Am J Pathol. 2015 Jan; 185(1):4-16.
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The enteric nervous system neuropeptide, bombesin, reverses innate immune impairments during parenteral nutrition. Ann Surg. 2014 Sep; 260(3):432-43; discussion 443-4.
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Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis. Gut. 2015 Jul; 64(7):1082-94.
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Parenteral nutrition decreases paneth cell function and intestinal bactericidal activity while increasing susceptibility to bacterial enteroinvasion. JPEN J Parenter Enteral Nutr. 2014 Sep; 38(7):817-824.
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Human ß-defensin 3 peptide is increased and redistributed in Crohn's ileitis. Inflamm Bowel Dis. 2013 Apr; 19(5):942-53.