Synaptosomal-Associated Protein 25
"Synaptosomal-Associated Protein 25" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous target SNARE protein that interacts with SYNTAXIN and SYNAPTOBREVIN. It is a core component of the machinery for intracellular MEMBRANE FUSION. The sequence contains 2 SNARE domains, one is the prototype for the Qb-SNARES, and the other is the prototype for the Qc-SNARES.
| Descriptor ID |
D050825
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| MeSH Number(s) |
D12.776.543.512.249.500.750.500 D12.776.543.512.249.500.875.500 D12.776.543.990.775.500.750.500 D12.776.543.990.775.500.875.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synaptosomal-Associated Protein 25".
Below are MeSH descriptors whose meaning is more specific than "Synaptosomal-Associated Protein 25".
This graph shows the total number of publications written about "Synaptosomal-Associated Protein 25" by people in this website by year, and whether "Synaptosomal-Associated Protein 25" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Synaptosomal-Associated Protein 25" by people in Profiles.
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A role for alternative splicing in circadian control of exocytosis and glucose homeostasis. Genes Dev. 2020 08 01; 34(15-16):1089-1105.
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Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene-based tests, genome-wide variation, and SNP heritability. Am J Med Genet B Neuropsychiatr Genet. 2017 Jun; 174(4):458-466.
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Complexin induces a conformational change at the membrane-proximal C-terminal end of the SNARE complex. Elife. 2016 06 02; 5.
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Interaction of anesthetics with neurotransmitter release machinery proteins. J Neurophysiol. 2013 Feb; 109(3):758-67.
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Distribution of the SNAP25 and SNAP23 synaptosomal-associated protein isoforms in rat cerebellar cortex. Neuroscience. 2009 Dec 15; 164(3):1084-96.
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A potent peptidomimetic inhibitor of botulinum neurotoxin serotype A has a very different conformation than SNAP-25 substrate. Structure. 2008 Oct 08; 16(10):1588-97.
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Stable silencing of SNAP-25 in PC12 cells by RNA interference. BMC Neurosci. 2006 Jan 30; 7:9.
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SNARE-mediated lipid mixing depends on the physical state of the vesicles. Biophys J. 2006 Mar 15; 90(6):2062-74.
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Volatile anesthetics bind rat synaptic snare proteins. Anesthesiology. 2005 Oct; 103(4):768-78.
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Labeling and quantifying sites of protein palmitoylation. Biotechniques. 2004 Feb; 36(2):276-85.