"Centrosome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The cell center, consisting of a pair of CENTRIOLES surrounded by a cloud of amorphous material called the pericentriolar region. During interphase, the centrosome nucleates microtubule outgrowth. The centrosome duplicates and, during mitosis, separates to form the two poles of the mitotic spindle (MITOTIC SPINDLE APPARATUS).
| Descriptor ID |
D018385
|
| MeSH Number(s) |
A11.284.430.214.190.750.585.160 A11.284.430.214.190.750.820.500.500
|
| Concept/Terms |
Pericentriolar Region- Pericentriolar Region
- Pericentriolar Regions
- Region, Pericentriolar
- Regions, Pericentriolar
|
Below are MeSH descriptors whose meaning is more general than "Centrosome".
Below are MeSH descriptors whose meaning is more specific than "Centrosome".
This graph shows the total number of publications written about "Centrosome" by people in this website by year, and whether "Centrosome" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Centrosome" by people in Profiles.
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Pathogenic Variants in CEP85L Cause Sporadic and Familial Posterior Predominant Lissencephaly. Neuron. 2020 04 22; 106(2):237-245.e8.
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Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity. Nat Microbiol. 2019 01; 4(1):164-176.
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Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25; 166(5):1147-1162.e15.
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Toxoplasma gondii Arginine Methyltransferase 1 (PRMT1) Is Necessary for Centrosome Dynamics during Tachyzoite Cell Division. mBio. 2016 Feb 02; 7(1):e02094-15.
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Mutations in CENPE define a novel kinetochore-centromeric mechanism for microcephalic primordial dwarfism. Hum Genet. 2014 Aug; 133(8):1023-39.
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Niche-associated activation of rac promotes the asymmetric division of Drosophila female germline stem cells. PLoS Biol. 2012; 10(7):e1001357.
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Some observations on the geometry of megakaryocyte mitotic figures: Buckyballs in the bone marrow. Blood. 2011 Dec 08; 118(24):6473-4.
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Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C. Cancer Res. 2010 Jun 15; 70(12):5085-95.
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Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplification. Cancer Res. 2010 Jun 15; 70(12):5074-84.
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SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice. Neuron. 2009 Oct 29; 64(2):173-87.