Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes.

Developmental defects and impaired network excitability in a cerebral organoid model of KCNJ11 p.V59M-related neonatal diabetes. Sci Rep. 2021 11 03; 11(1):21590.

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subject areas

Adult
Brain
Cell Culture Techniques
Diabetes Mellitus
Electrophysiology
Female
Fibroblasts
Humans
In Vitro Techniques
Induced Pluripotent Stem Cells
Infant, Newborn
Infant, Newborn, Diseases
Leukocytes, Mononuclear
Microscopy, Confocal
Nerve Net
Neural Pathways
Organoids
Patch-Clamp Techniques
Potassium Channels, Inwardly Rectifying

authors with profiles

Louis Philipson
Siri Atma W. Greeley
Andrew K. Tryba
Alfredo Garcia