Eukaryotic Initiation Factor-4E
"Eukaryotic Initiation Factor-4E" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptide initiation factor that binds specifically to the 5' MRNA CAP STRUCTURE of MRNA in the CYTOPLASM. It is a component of the trimeric complex EIF4F.
| Descriptor ID |
D039561
|
| MeSH Number(s) |
D12.776.157.725.750.374 D12.776.835.725.868.500.750
|
| Concept/Terms |
Eukaryotic Initiation Factor-4E- Eukaryotic Initiation Factor-4E
- Eukaryotic Initiation Factor 4E
- Factor-4E, Eukaryotic Initiation
- Initiation Factor-4E, Eukaryotic
- Peptide Initiation Factor EIF-4E
- Peptide Initiation Factor EIF 4E
- EIF4E
- Eukaryotic Peptide Initiation Factor-4E
- Eukaryotic Peptide Initiation Factor 4E
- CDC33 Gene Product
- EIF-4E
- EIF 4E
|
Below are MeSH descriptors whose meaning is more general than "Eukaryotic Initiation Factor-4E".
Below are MeSH descriptors whose meaning is more specific than "Eukaryotic Initiation Factor-4E".
This graph shows the total number of publications written about "Eukaryotic Initiation Factor-4E" by people in this website by year, and whether "Eukaryotic Initiation Factor-4E" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2017 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Eukaryotic Initiation Factor-4E" by people in Profiles.
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Crystal structure of a cap-independent translation enhancer RNA. Nucleic Acids Res. 2023 09 08; 51(16):8891-8907.
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Loss of mTORC1 signalling impairs ß-cell homeostasis and insulin processing. Nat Commun. 2017 07 12; 8:16014.
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The eIF4E inhibitor ribavirin as a potential antilymphoma therapeutic: early clinical data. Leuk Lymphoma. 2018 01; 59(1):256-258.
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Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs. Mol Cell Biol. 2015 Nov; 35(22):3921-32.
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The translational regulator Cup controls NMJ presynaptic terminal morphology. Mol Cell Neurosci. 2015 Jul; 67:126-36.
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Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors. J Biol Chem. 2013 Aug 16; 288(33):23814-22.
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The cap-binding translation initiation factor, eIF4E, binds a pseudoknot in a viral cap-independent translation element. Structure. 2011 Jun 08; 19(6):868-80.
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Stress granule formation mediates the inhibition of colonic Hsp70 translation by interferon-gamma and tumor necrosis factor-alpha. Am J Physiol Gastrointest Liver Physiol. 2010 Apr; 298(4):G481-92.
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4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. Am J Respir Cell Mol Biol. 2005 Aug; 33(2):195-202.
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Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase. J Biol Chem. 2000 Apr 14; 275(15):10779-87.