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Xianzun Tao

TitleResearch Assistant Professor
InstitutionUniversity of Chicago
DepartmentNeurology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lobato AG, Ortiz-Vega N, Canic T, Tao X, Bucan N, Ruan K, Rebelo AP, Schule R, Zuchner S, Syed S, Zhai RG. Loss of Fic causes progressive neurodegeneration in a Drosophila model of hereditary spastic paraplegia. Biochim Biophys Acta Mol Basis Dis. 2024 10; 1870(7):167348. PMID: 38986817; PMCID: PMC11549967.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Tao X, Liu J, Diaz-Perez Z, Foley JR, Nwafor A, Stewart TM, Casero RA, Zhai RG. Reduction of spermine synthase enhances autophagy to suppress Tau accumulation. Cell Death Dis. 2024 May 13; 15(5):333. PMID: 38740758; PMCID: PMC11091227.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    3. Stewart TM, Foley JR, Holbert CE, Khomutov M, Rastkari N, Tao X, Khomutov AR, Zhai RG, Casero RA. Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome. EMBO Mol Med. 2023 11 08; 15(11):e17833. PMID: 37702369; PMCID: PMC10630878.
      Citations: 7     Fields:    Translation:Humans
    4. Zhu Y, Lobato AG, Rebelo AP, Canic T, Ortiz-Vega N, Tao X, Syed S, Yanick C, Saporta M, Shy M, Perfetti R, Shendelman S, Züchner S, Zhai RG. Sorbitol reduction via govorestat ameliorates synaptic dysfunction and neurodegeneration in sorbitol dehydrogenase deficiency. JCI Insight. 2023 05 22; 8(10). PMID: 37014713; PMCID: PMC10322690.
      Citations: 6     Fields:    Translation:Humans
    5. Tao X, Zhu Y, Diaz-Perez Z, Yu SH, Foley JR, Stewart TM, Casero RA, Steet R, Zhai RG. Phenylbutyrate modulates polyamine acetylase and ameliorates Snyder-Robinson syndrome in a Drosophila model and patient cells. JCI Insight. 2022 07 08; 7(13). PMID: 35801587; PMCID: PMC9310527.
      Citations: 7     Fields:    Translation:Animals
    6. Liu J, Tao X, Zhu Y, Li C, Ruan K, Diaz-Perez Z, Rai P, Wang H, Zhai RG. NMNAT promotes glioma growth through regulating post-translational modifications of P53 to inhibit apoptosis. Elife. 2021 12 17; 10. PMID: 34919052; PMCID: PMC8683086.
      Citations: 12     Fields:    Translation:AnimalsCells
    7. Tantak MP, Sekhar V, Tao X, Zhai RG, Phanstiel O. Development of a Redox-Sensitive Spermine Prodrug for the Potential Treatment of Snyder Robinson Syndrome. J Med Chem. 2021 11 11; 64(21):15593-15607. PMID: 34695351; PMCID: PMC9115777.
      Citations: 5     Fields:    Translation:AnimalsCells
    8. Zhu Y, Li C, Tao X, Brazill JM, Park J, Diaz-Perez Z, Zhai RG. Nmnat restores neuronal integrity by neutralizing mutant Huntingtin aggregate-induced progressive toxicity. Proc Natl Acad Sci U S A. 2019 09 17; 116(38):19165-19175. PMID: 31484760; PMCID: PMC6754563.
      Citations: 18     Fields:    Translation:Animals
    9. Park J, Zhu Y, Tao X, Brazill JM, Li C, Wuchty S, Zhai RG. MicroRNA miR-1002 Enhances NMNAT-Mediated Stress Response by Modulating Alternative Splicing. iScience. 2019 Sep 27; 19:1048-1064. PMID: 31522116; PMCID: PMC6745518.
      Citations: 1     
    10. Wang M, Tao X, Jacob MD, Bennett CA, Ho JJD, Gonzalgo ML, Audas TE, Lee S. Stress-Induced Low Complexity RNA Activates Physiological Amyloidogenesis. Cell Rep. 2018 08 14; 24(7):1713-1721.e4. PMID: 30110628; PMCID: PMC6249693.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    11. Tao X, Gao G. Tristetraprolin Recruits Eukaryotic Initiation Factor 4E2 To Repress Translation of AU-Rich Element-Containing mRNAs. Mol Cell Biol. 2015 Nov; 35(22):3921-32. PMID: 26370510; PMCID: PMC4609744.
      Citations: 26     Fields:    Translation:HumansCells
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