"Dystroglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dystrophin-associated proteins that play role in the formation of a transmembrane link between laminin-2 and DYSTROPHIN. Both the alpha and the beta subtypes of dystroglycan originate via POST-TRANSLATIONAL PROTEIN PROCESSING of a single precursor protein.
Descriptor ID |
D049030
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MeSH Number(s) |
D12.776.210.500.410.500 D12.776.220.362.249 D12.776.543.268.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Dystroglycans".
Below are MeSH descriptors whose meaning is more specific than "Dystroglycans".
This graph shows the total number of publications written about "Dystroglycans" by people in this website by year, and whether "Dystroglycans" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2001 | 0 | 2 | 2 |
2002 | 0 | 1 | 1 |
2003 | 0 | 3 | 3 |
2008 | 1 | 0 | 1 |
2011 | 0 | 1 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2017 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Dystroglycans" by people in Profiles.
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The Molecular Basis and Biologic Significance of the ß-Dystroglycan-Emerin Interaction. Int J Mol Sci. 2020 Aug 19; 21(17).
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Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation. Development. 2020 04 08; 147(7).
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Walker-Warburg syndrome and tectocerebellar dysraphia: A novel association caused by a homozygous DAG1 mutation. Eur J Paediatr Neurol. 2018 May; 22(3):525-531.
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Mutations in B3GALNT2 cause congenital muscular dystrophy and hypoglycosylation of a-dystroglycan. Am J Hum Genet. 2013 Mar 07; 92(3):354-65.
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ISPD loss-of-function mutations disrupt dystroglycan O-mannosylation and cause Walker-Warburg syndrome. Nat Genet. 2012 May; 44(5):575-80.
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LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin. Hum Genet. 2012 Jul; 131(7):1123-35.
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Stretch-induced activation of AMP kinase in the lung requires dystroglycan. Am J Respir Cell Mol Biol. 2008 Dec; 39(6):666-72.
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Genetic compensation for sarcoglycan loss by integrin alpha7beta1 in muscle. J Cell Sci. 2004 Aug 01; 117(Pt 17):3821-30.
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The dystrophin glycoprotein complex: signaling strength and integrity for the sarcolemma. Circ Res. 2004 Apr 30; 94(8):1023-31.
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N-terminal alpha-dystroglycan binds to different extracellular matrix molecules expressed in regenerating peripheral nerves in a protein-mediated manner and promotes neurite extension of PC12 cells. Mol Cell Neurosci. 2003 Dec; 24(4):1062-73.