Tissue Inhibitor of Metalloproteinase-1
"Tissue Inhibitor of Metalloproteinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
| Descriptor ID |
D019715
|
| MeSH Number(s) |
D12.776.645.875.450
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinase-1".
Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinase-1".
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in this website by year, and whether "Tissue Inhibitor of Metalloproteinase-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in Profiles.
-
Mutant MMP-9 and HGF gene transfer enhance resolution of CCl4-induced liver fibrosis in rats: role of ASH1 and EZH2 methyltransferases repression. PLoS One. 2014; 9(11):e112384.
-
Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod. 2013 Sep; 28(9):2407-16.
-
Global gene expression profiling in PAI-1 knockout murine heart and kidney: molecular basis of cardiac-selective fibrosis. PLoS One. 2013; 8(5):e63825.
-
Changes in TIMP-1 and -2 expression in the early stage of porcine serum-induced liver fibrosis in rats. Exp Toxicol Pathol. 2011 May; 63(4):357-61.
-
MMP inhibition blocks fibroblast-dependent skin cancer invasion, reduces vascularization and alters VEGF-A and PDGF-BB expression. Anticancer Res. 2010 Mar; 30(3):703-11.
-
Chronic treatment with clenbuterol modulates endothelial progenitor cells and circulating factors in a murine model of cardiomyopathy. J Cardiovasc Transl Res. 2009 Jun; 2(2):182-90.
-
Pre-ischemic exercise reduces matrix metalloproteinase-9 expression and ameliorates blood-brain barrier dysfunction in stroke. Neuroscience. 2008 Jan 24; 151(2):340-51.
-
MMP25 (MT6-MMP) is highly expressed in human colon cancer, promotes tumor growth, and exhibits unique biochemical properties. J Biol Chem. 2007 Jul 27; 282(30):21998-2010.
-
Signal transducers and activators of transcription-3 up-regulates tissue inhibitor of metalloproteinase-1 expression and decreases invasiveness of breast cancer. Am J Pathol. 2006 Aug; 169(2):633-42.
-
Association of E-cadherin, matrix metalloproteinases, and tissue inhibitors of metalloproteinases with the progression and metastasis of hepatocellular carcinoma. Mod Pathol. 2006 Apr; 19(4):533-40.