"Caspase 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
| Descriptor ID |
D053454
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| MeSH Number(s) |
D08.811.277.656.262.500.126.550.920 D08.811.277.656.300.200.126.550.920 D12.644.360.075.405.550.920 D12.776.476.075.405.550.920
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Caspase 12".
Below are MeSH descriptors whose meaning is more specific than "Caspase 12".
This graph shows the total number of publications written about "Caspase 12" by people in this website by year, and whether "Caspase 12" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 12" by people in Profiles.
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Reciprocal modulation of C/EBP-a and C/EBP-ß by IL-13 in activated microglia prevents neuronal death. Eur J Immunol. 2013 Nov; 43(11):2854-65.
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Enhancement of cisplatin [cis-diammine dichloroplatinum (II)] cytotoxicity by O6-benzylguanine involves endoplasmic reticulum stress. J Pharmacol Exp Ther. 2008 Nov; 327(2):442-52.