Pyruvate Dehydrogenase (Lipoamide)
"Pyruvate Dehydrogenase (Lipoamide)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The E1 component of the multienzyme PYRUVATE DEHYDROGENASE COMPLEX. It is composed of 2 alpha subunits (pyruvate dehydrogenase E1 alpha subunit) and 2 beta subunits (pyruvate dehydrogenase E1 beta subunit).
| Descriptor ID |
D030481
|
| MeSH Number(s) |
D05.500.562.625.875 D08.811.600.741.725 D08.811.682.657.350.875
|
| Concept/Terms |
Pyruvate Dehydrogenase (Lipoamide)- Pyruvate Dehydrogenase (Lipoamide)
- Pyruvate Dehydrogenase-E1
- Pyruvate Dehydrogenase E1
- Pyruvate Decarboxylase (Lipoamide)
- Pyruvate Dehydrogenase Component E1
|
Below are MeSH descriptors whose meaning is more general than "Pyruvate Dehydrogenase (Lipoamide)".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Dehydrogenase (Lipoamide)".
This graph shows the total number of publications written about "Pyruvate Dehydrogenase (Lipoamide)" by people in this website by year, and whether "Pyruvate Dehydrogenase (Lipoamide)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Dehydrogenase (Lipoamide)" by people in Profiles.
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Tyr-301 phosphorylation inhibits pyruvate dehydrogenase by blocking substrate binding and promotes the Warburg effect. J Biol Chem. 2014 Sep 19; 289(38):26533-26541.
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Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Mol Cell. 2014 Feb 20; 53(4):534-48.