"Cyclophilins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of peptidyl-prolyl cis-trans isomerases that bind to CYCLOSPORINS and regulate the IMMUNE SYSTEM. EC 5.2.1.-
| Descriptor ID |
D021983
|
| MeSH Number(s) |
D08.811.399.325.500.400.300 D12.776.543.750.705.400.300 D12.776.827.275.300
|
| Concept/Terms |
Cyclophilins- Cyclophilins
- Cyclosporin-Binding Proteins
- Cyclosporin Binding Proteins
- Proteins, Cyclosporin-Binding
- Cyclophilin
- Cyclosporin-Binding Protein
- Cyclosporin Binding Protein
- Protein, Cyclosporin-Binding
|
Below are MeSH descriptors whose meaning is more general than "Cyclophilins".
Below are MeSH descriptors whose meaning is more specific than "Cyclophilins".
This graph shows the total number of publications written about "Cyclophilins" by people in this website by year, and whether "Cyclophilins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2010 | 1 | 2 | 3 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclophilins" by people in Profiles.
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Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer. Nat Commun. 2016 04 27; 7:11375.
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ROS-mediated PARP activity undermines mitochondrial function after permeability transition pore opening during myocardial ischemia-reperfusion. J Am Heart Assoc. 2013 Apr 18; 2(2):e000159.
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Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature. 2010 Dec 02; 468(7324):696-700.
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Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis. Free Radic Biol Med. 2010 Dec 15; 49(12):1925-36.
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Epithelial cell death is an important contributor to oxidant-mediated acute lung injury. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1043-54.
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Targeting cyclophilin D and the mitochondrial permeability transition enhances beta-cell survival and prevents diabetes in Pdx1 deficiency. Proc Natl Acad Sci U S A. 2010 Jun 01; 107(22):10214-9.
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Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage. J Biol Chem. 2010 Jul 16; 285(29):22461-72.
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Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization. Cancer Res. 2008 Aug 01; 68(15):6199-207.
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Genetic and pharmacologic inhibition of mitochondrial-dependent necrosis attenuates muscular dystrophy. Nat Med. 2008 Apr; 14(4):442-7.
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Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis. Mol Cell Biol. 2006 Mar; 26(6):2215-25.