"SUMO-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 1.5-kDa small ubiquitin-related modifier protein that can covalently bind via an isopeptide link to a number of cellular proteins. It may play a role in intracellular protein transport and a number of other cellular processes.
Descriptor ID |
D025842
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MeSH Number(s) |
D12.776.947.249.500
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Concept/Terms |
SUMO-1 Protein- SUMO-1 Protein
- SUMO 1 Protein
- Gap-modifying Protein 1
- Gap modifying Protein 1
- PIC 1 Protein
- PIC1 Protein
- Ubiquitin-like 1 Gene Product
- Ubiquitin like 1 Gene Product
- Protein GMP1
- GMP1, Protein
- Sentrin
- Sentrin 1
- SMT3C Protein
- SUMO Protein
- UBL1 Protein
- PML-Interacting Clone Protein
- PML Interacting Clone Protein
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Below are MeSH descriptors whose meaning is more general than "SUMO-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "SUMO-1 Protein".
This graph shows the total number of publications written about "SUMO-1 Protein" by people in this website by year, and whether "SUMO-1 Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2009 | 0 | 2 | 2 |
2010 | 1 | 0 | 1 |
2011 | 2 | 3 | 5 |
2013 | 1 | 0 | 1 |
2014 | 0 | 1 | 1 |
2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "SUMO-1 Protein" by people in Profiles.
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PPAR?-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):12102-12111.
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Sumoylated HSP90 is a dominantly inherited plasma cell dyscrasias risk factor. J Clin Invest. 2015 Jan; 125(1):316-23.
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De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ Res. 2013 Mar 15; 112(6):911-23.
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Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar; 52(3):638-49.
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PKC? mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation. J Cell Biol. 2011 May 30; 193(5):867-84.
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Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76.
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SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons. J Gen Physiol. 2011 May; 137(5):441-54.
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Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7751-6.
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One SUMO is sufficient to silence the dimeric potassium channel K2P1. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10743-8.
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Rational conversion of affinity reagents into label-free sensors for Peptide motifs by designed allostery. ACS Chem Biol. 2010 Mar 19; 5(3):273-7.