Small Ubiquitin-Related Modifier Proteins
"Small Ubiquitin-Related Modifier Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of structurally related proteins of 12-20 kDa in size. They covalently modify specific proteins in a manner analogous to UBIQUITIN.
| Descriptor ID |
D025841
|
| MeSH Number(s) |
D12.776.947.249
|
| Concept/Terms |
Small Ubiquitin-Related Modifier Proteins- Small Ubiquitin-Related Modifier Proteins
- Small Ubiquitin Related Modifier Proteins
- Ubiquitin-Related Modifier Protein, Small
- Ubiquitin Related Modifier Protein, Small
- Sentrins
- Sentrin Proteins
- SUMO Proteins
|
Below are MeSH descriptors whose meaning is more general than "Small Ubiquitin-Related Modifier Proteins".
Below are MeSH descriptors whose meaning is more specific than "Small Ubiquitin-Related Modifier Proteins".
This graph shows the total number of publications written about "Small Ubiquitin-Related Modifier Proteins" by people in this website by year, and whether "Small Ubiquitin-Related Modifier Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Small Ubiquitin-Related Modifier Proteins" by people in Profiles.
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Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury. J Clin Invest. 2019 02 01; 129(2):786-801.
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De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis. Circ Res. 2013 Mar 15; 112(6):911-23.
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Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity. Arterioscler Thromb Vasc Biol. 2013 Feb; 33(2):321-9.
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SUMO downregulates GLP-1-stimulated cAMP generation and insulin secretion. Am J Physiol Endocrinol Metab. 2012 Mar 15; 302(6):E714-23.
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Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects. PLoS One. 2011; 6(6):e20803.
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Isoform-specific monobody inhibitors of small ubiquitin-related modifiers engineered using structure-guided library design. Proc Natl Acad Sci U S A. 2011 May 10; 108(19):7751-6.
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SUMO modification regulates BLM and RAD51 interaction at damaged replication forks. PLoS Biol. 2009 Dec; 7(12):e1000252.
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Sumoylation silences the plasma membrane leak K+ channel K2P1. Cell. 2005 Apr 08; 121(1):37-47.