"Erdheim-Chester Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rare form of non-Langerhans-cell histiocytosis (HISTIOCYTOSIS, NON-LANGERHANS-CELL) with onset in middle age. The systemic disease is characterized by infiltration of lipid-laden macrophages, multinucleated giant cells, an inflammatory infiltrate of lymphocytes and histiocytes in the bone marrow, and a generalized sclerosis of the long bones.
Descriptor ID |
D031249
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MeSH Number(s) |
C15.604.250.410.224
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Erdheim-Chester Disease".
Below are MeSH descriptors whose meaning is more specific than "Erdheim-Chester Disease".
This graph shows the total number of publications written about "Erdheim-Chester Disease" by people in this website by year, and whether "Erdheim-Chester Disease" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2004 | 1 | 0 | 1 |
2016 | 1 | 0 | 1 |
2017 | 2 | 1 | 3 |
2019 | 1 | 0 | 1 |
2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Erdheim-Chester Disease" by people in Profiles.
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Neurologic and oncologic features of Erdheim-Chester disease: a 30-patient series. Neuro Oncol. 2020 07 07; 22(7):979-992.
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Neurological manifestations of Erdheim-Chester Disease. Ann Clin Transl Neurol. 2020 04; 7(4):497-506.
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Erdheim-Chester disease with concomitant Rosai-Dorfman like lesions: a distinct entity mainly driven by MAP2K1. Haematologica. 2020 01; 105(1):e5-e8.
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The histopathology of Erdheim-Chester disease: a comprehensive review of a molecularly characterized cohort. Mod Pathol. 2018 04; 31(4):581-597.
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High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis. Blood. 2017 08 24; 130(8):1007-1013.
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Functional evidence for derivation of systemic histiocytic neoplasms from hematopoietic stem/progenitor cells. Blood. 2017 07 13; 130(2):176-180.
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Anakinra as efficacious therapy for 2 cases of intracranial Erdheim-Chester disease. Blood. 2016 10 06; 128(14):1896-1898.
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Diagnosis of Erdheim-Chester disease by using computerized tomography-guided stereotactic biopsy of a caudate lesion. Case report. J Neurosurg. 2004 Sep; 101(3):521-7.