Early Growth Response Protein 1
"Early Growth Response Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An early growth response transcription factor and zinc finger protein that has been implicated in regulation of CELL PROLIFERATION and APOPTOSIS.
| Descriptor ID |
D051766
|
| MeSH Number(s) |
D12.776.260.158.500 D12.776.460.525.500 D12.776.930.213.500
|
| Concept/Terms |
Early Growth Response Protein 1- Early Growth Response Protein 1
- Znf225 Protein
- Protein, Znf225
- Early Growth Response Transcription Factor 1
- EGR1 Transcription Factor
- Transcription Factor, EGR1
- Zinc Finger Protein 225
|
Below are MeSH descriptors whose meaning is more general than "Early Growth Response Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Early Growth Response Protein 1".
This graph shows the total number of publications written about "Early Growth Response Protein 1" by people in this website by year, and whether "Early Growth Response Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 3 | 3 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2018 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Early Growth Response Protein 1" by people in Profiles.
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EGR1 Haploinsufficiency Confers a Fitness Advantage to Hematopoietic Stem Cells Following Chemotherapy. Exp Hematol. 2022 11; 115:54-67.
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Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children. J Allergy Clin Immunol. 2021 12; 148(6):1505-1514.
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Bcl11b controls odorant receptor class choice in mice. Commun Biol. 2019; 2:296.
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The NCI Transcriptional Pharmacodynamics Workbench: A Tool to Examine Dynamic Expression Profiling of Therapeutic Response in the NCI-60 Cell Line Panel. Cancer Res. 2018 12 15; 78(24):6807-6817.
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Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice. Blood. 2014 Feb 13; 123(7):1069-78.
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Cell intrinsic and extrinsic factors synergize in mice with haploinsufficiency for Tp53, and two human del(5q) genes, Egr1 and Apc. Blood. 2014 Jan 09; 123(2):228-38.
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Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol. 2012 Feb 05; 13(3):264-71.
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Xanthine oxidase-derived ROS upregulate Egr-1 via ERK1/2 in PA smooth muscle cells; model to test impact of extracellular ROS in chronic hypoxia. PLoS One. 2011; 6(11):e27531.
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Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy. Cancer Gene Ther. 2008 Mar; 15(3):133-9.
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Haploinsufficiency of EGR1, a candidate gene in the del(5q), leads to the development of myeloid disorders. Blood. 2007 Jul 15; 110(2):719-26.