Interleukin-12 Subunit p40
"Interleukin-12 Subunit p40" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine subunit that is a component of both interleukin-12 and interleukin-23. It binds to the INTERLEUKIN-12 SUBUNIT P35 via a disulfide bond to form interleukin-12 and to INTERLEUKIN-23 SUBUNIT P19 to form interleukin-23.
| Descriptor ID |
D053762
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| MeSH Number(s) |
D12.644.276.374.465.512.500 D12.644.276.374.465.759.249 D12.776.467.374.465.512.500 D12.776.467.374.465.759.249 D23.529.374.465.512.500 D23.529.374.465.550.249
|
| Concept/Terms |
Interleukin-12 Subunit p40- Interleukin-12 Subunit p40
- Interleukin 12 Subunit p40
- Interleukin-23 Subunit p40
- Interleukin 23 Subunit p40
- p40, Interleukin-23 Subunit
- Interleukin-12,23 p40 Subunit
- Interleukin 12,23 p40 Subunit
- p40 Subunit, Interleukin-12,23
- Interleukin-12b
- Interleukin 12b
- IL-12p40
- Interleukin-12 beta Chain
- Chain, Interleukin-12 beta
- Interleukin 12 beta Chain
- beta Chain, Interleukin-12
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-12 Subunit p40".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-12 Subunit p40".
This graph shows the total number of publications written about "Interleukin-12 Subunit p40" by people in this website by year, and whether "Interleukin-12 Subunit p40" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-12 Subunit p40" by people in Profiles.
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Cryptococcus neoformans Evades Pulmonary Immunity by Modulating Xylose Precursor Transport. Infect Immun. 2020 07 21; 88(8).
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Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity. Arthritis Rheumatol. 2016 10; 68(10):2492-502.
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Genome-Wide Association Study Identifies African-Specific Susceptibility Loci in African Americans With Inflammatory Bowel Disease. Gastroenterology. 2017 01; 152(1):206-217.e2.
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Briakinumab for treatment of Crohn's disease: results of a randomized trial. Inflamm Bowel Dis. 2015 Jun; 21(6):1329-40.
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Toward an understanding of the gene-specific and global logic of inducible gene transcription. Cold Spring Harb Symp Quant Biol. 2013; 78:61-8.
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Francisella tularensis LVS-induced Interleukin-12 p40 cytokine production mediates dendritic cell migration through IL-12 Receptor ß1. Cytokine. 2011 Sep; 55(3):372-9.
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Dectin-1 diversifies Aspergillus fumigatus-specific T cell responses by inhibiting T helper type 1 CD4 T cell differentiation. J Exp Med. 2011 Feb 14; 208(2):369-81.
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The role of cytokines in the initiation, expansion, and control of cellular immunity to tuberculosis. Immunol Rev. 2008 Dec; 226:191-204.
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Yersinia pestis evades TLR4-dependent induction of IL-12(p40)2 by dendritic cells and subsequent cell migration. J Immunol. 2008 Oct 15; 181(8):5560-7.
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IL-12p40: an inherently agonistic cytokine. Trends Immunol. 2007 Jan; 28(1):33-8.