Group V Phospholipases A2
"Group V Phospholipases A2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.
| Descriptor ID |
D054505
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| MeSH Number(s) |
D08.811.277.352.100.680.750.937.750.775
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Group V Phospholipases A2".
Below are MeSH descriptors whose meaning is more specific than "Group V Phospholipases A2".
This graph shows the total number of publications written about "Group V Phospholipases A2" by people in this website by year, and whether "Group V Phospholipases A2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
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Below are the most recent publications written about "Group V Phospholipases A2" by people in Profiles.
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Group V phospholipase A2 mediates barrier disruption of human pulmonary endothelial cells caused by LPS in vitro. Am J Respir Cell Mol Biol. 2011 Mar; 44(3):361-8.
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Secretory group V phospholipase A2 regulates acute lung injury and neutrophilic inflammation caused by LPS in mice. Am J Physiol Lung Cell Mol Physiol. 2009 Jun; 296(6):L879-87.
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Transcellular secretion of group V phospholipase A2 from epithelium induces beta 2-integrin-mediated adhesion and synthesis of leukotriene C4 in eosinophils. J Immunol. 2006 Jul 01; 177(1):574-82.
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Human group V phospholipase A2 induces group IVA phospholipase A2-independent cysteinyl leukotriene synthesis in human eosinophils. J Biol Chem. 2003 Oct 03; 278(40):38813-20.
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Group V phospholipase A2 induces leukotriene biosynthesis in human neutrophils through the activation of group IVA phospholipase A2. J Biol Chem. 2002 Sep 27; 277(39):36479-88.
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Quantitation of secretory group V phospholipase A(2) in human tissues by sandwich enzyme-linked immunosorbent assay. J Immunol Methods. 2002 Apr 01; 262(1-2):41-51.
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Characterization of monoclonal antibodies specific for 14-kDa human group V secretory phospholipase A2 (hVPLA2). Hybridoma. 2000 Apr; 19(2):171-6.