"Twist-Related Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A basic helix-loop-helix transcription factor that was originally identified in DROSOPHILA as essential for proper gastrulation and MESODERM formation. It plays an important role in EMBRYONIC DEVELOPMENT and CELL DIFFERENTIATION of MUSCLE CELLS, and is found in a wide variety of organisms.
| Descriptor ID |
D051879
|
| MeSH Number(s) |
D12.776.260.103.906.250 D12.776.930.125.906.250
|
| Concept/Terms |
Twist-Related Protein 1- Twist-Related Protein 1
- Twist Related Protein 1
- Twist Transcription Factor
- Transcription Factor, Twist
- Twist Protein
- TWIST1 Protein
- Twist Family Bhlh Transcription Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Twist-Related Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Twist-Related Protein 1".
This graph shows the total number of publications written about "Twist-Related Protein 1" by people in this website by year, and whether "Twist-Related Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 1 | 2 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 3 | 0 | 3 |
| 2015 | 1 | 1 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Twist-Related Protein 1" by people in Profiles.
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Twist promotes tumor metastasis in basal-like breast cancer by transcriptionally upregulating ROR1. Theranostics. 2018; 8(10):2739-2751.
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ADAM12 induction by Twist1 promotes tumor invasion and metastasis via regulation of invadopodia and focal adhesions. J Cell Sci. 2017 Jun 15; 130(12):2036-2048.
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Autophagy positively regulates DNA damage recognition by nucleotide excision repair. Autophagy. 2016; 12(2):357-68.
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Twist-BRD4 complex: potential drug target for basal-like breast cancer. Curr Pharm Des. 2015; 21(10):1256-61.
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Autophagy deficiency stabilizes TWIST1 to promote epithelial-mesenchymal transition. Autophagy. 2014 Oct 01; 10(10):1864-5.
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Regulation of cell proliferation and migration by p62 through stabilization of Twist1. Proc Natl Acad Sci U S A. 2014 Jun 24; 111(25):9241-6.
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Disrupting the interaction of BRD4 with diacetylated Twist suppresses tumorigenesis in basal-like breast cancer. Cancer Cell. 2014 Feb 10; 25(2):210-25.
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Distinct Caenorhabditis elegans HLH-8/twist-containing dimers function in the mesoderm. Dev Dyn. 2012 Mar; 241(3):481-92.
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Targeting invadopodia to block breast cancer metastasis. Oncotarget. 2011 Jul; 2(7):562-8.
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Twist1-induced invadopodia formation promotes tumor metastasis. Cancer Cell. 2011 Mar 08; 19(3):372-86.