"Telomere Shortening" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
| Descriptor ID |
D059506
|
| MeSH Number(s) |
G02.111.225.940 G04.043.630 G05.226.940
|
| Concept/Terms |
Telomere Shortening- Telomere Shortening
- Shortening, Telomere
- Shortenings, Telomere
- Telomere Shortenings
|
Below are MeSH descriptors whose meaning is more general than "Telomere Shortening".
Below are MeSH descriptors whose meaning is more specific than "Telomere Shortening".
This graph shows the total number of publications written about "Telomere Shortening" by people in this website by year, and whether "Telomere Shortening" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 3 | 4 |
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Below are the most recent publications written about "Telomere Shortening" by people in Profiles.
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Lung transplantation for idiopathic pulmonary fibrosis enriches for individuals with telomere-mediated disease. J Heart Lung Transplant. 2022 05; 41(5):654-663.
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Urinary arsenic and relative telomere length in 5-7 year old children in Bangladesh. Environ Int. 2021 11; 156:106765.
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RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function. J Hum Genet. 2021 Nov; 66(11):1101-1112.
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The nuclear sirtuin SIRT6 protects the heart from developing aging-associated myocyte senescence and cardiac hypertrophy. Aging (Albany NY). 2021 05 02; 13(9):12334-12358.
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Determinants of telomere length across human tissues. Science. 2020 09 11; 369(6509).
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Short lymphocyte, but not granulocyte, telomere length in a subset of patients with systemic sclerosis. Ann Rheum Dis. 2019 08; 78(8):1142-1144.
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A novel pooled-sample multiplex luminex assay for high-throughput measurement of relative telomere length. Am J Hum Biol. 2018 07; 30(4):e23118.
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Heterozygous RTEL1 variants in bone marrow failure and myeloid neoplasms. Blood Adv. 2018 01 09; 2(1):36-48.
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Sex-Specific and Time-Varying Associations Between Cigarette Smoking and Telomere Length Among Older Adults. Am J Epidemiol. 2016 12 15; 184(12):922-932.
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Measurement of telomere length: a new assay using QuantiGene chemistry on a Luminex platform. Cancer Epidemiol Biomarkers Prev. 2014 Dec; 23(12):2667-72.