Receptors, Adrenergic, beta-1
"Receptors, Adrenergic, beta-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-1 receptors are equally sensitive to EPINEPHRINE and NOREPINEPHRINE and bind the agonist DOBUTAMINE and the antagonist METOPROLOL with high affinity. They are found in the HEART, juxtaglomerular cells, and in the central and peripheral nervous systems.
| Descriptor ID |
D018342
|
| MeSH Number(s) |
D12.776.543.750.670.300.300.340.100 D12.776.543.750.695.150.300.340.700 D12.776.543.750.720.330.300.340.100
|
| Concept/Terms |
Receptors, Adrenergic, beta-1- Receptors, Adrenergic, beta-1
- Receptor, Adrenergic, beta-1
- Receptors, beta-1 Adrenergic
- Receptors, beta 1 Adrenergic
- beta-1 Adrenergic Receptors
- Adrenergic Receptors, beta-1
- beta 1 Adrenergic Receptors
- Adrenergic beta-1 Receptors
- Adrenergic beta 1 Receptors
- Receptors, Adrenergic beta-1
- beta-1 Receptors, Adrenergic
- Adrenergic Receptor, beta-1
- Adrenergic Receptor, beta 1
- Receptor, beta-1 Adrenergic
- beta-1 Adrenergic Receptor
- beta 1 Adrenergic Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Adrenergic, beta-1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Catecholamine [D12.776.543.750.670.300]
- Receptors, Adrenergic [D12.776.543.750.670.300.300]
- Receptors, Adrenergic, beta [D12.776.543.750.670.300.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.670.300.300.340.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Catecholamine [D12.776.543.750.695.150]
- Receptors, Adrenergic [D12.776.543.750.695.150.300]
- Receptors, Adrenergic, beta [D12.776.543.750.695.150.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.695.150.300.340.700]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Catecholamine [D12.776.543.750.720.330]
- Receptors, Adrenergic [D12.776.543.750.720.330.300]
- Receptors, Adrenergic, beta [D12.776.543.750.720.330.300.340]
- Receptors, Adrenergic, beta-1 [D12.776.543.750.720.330.300.340.100]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Adrenergic, beta-1".
This graph shows the total number of publications written about "Receptors, Adrenergic, beta-1" by people in this website by year, and whether "Receptors, Adrenergic, beta-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 1 | 2 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 2 | 2 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptors, Adrenergic, beta-1" by people in Profiles.
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Bucindolol Decreases Atrial Fibrillation Burden in Patients With Heart Failure and the ADRB1 Arg389Arg Genotype. Circ Arrhythm Electrophysiol. 2021 08; 14(8):e009591.
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ß2 -Adrenergic Receptor Gene Affects the Heart Rate Response of ß-Blockers: Evidence From 3 Clinical Studies. J Clin Pharmacol. 2019 11; 59(11):1462-1470.
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Bucindolol for the Maintenance of Sinus Rhythm in a Genotype-Defined HF Population: The GENETIC-AF Trial. JACC Heart Fail. 2019 07; 7(7):586-598.
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A genotype-directed comparative effectiveness trial of Bucindolol and metoprolol succinate for prevention of symptomatic atrial fibrillation/atrial flutter in patients with heart failure: Rationale and design of the GENETIC-AF trial. Am Heart J. 2018 05; 199:51-58.
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Genetic variation in alpha2-adrenoreceptors and heart rate recovery after exercise. Physiol Genomics. 2015 Sep; 47(9):400-6.
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ß2-Adrenergic agonists augment air pollution-induced IL-6 release and thrombosis. J Clin Invest. 2014 Jul; 124(7):2935-46.
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Prevention of atrial fibrillation by bucindolol is dependent on the beta1389 Arg/Gly adrenergic receptor polymorphism. JACC Heart Fail. 2013 Aug; 1(4):338-344.
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Adrenergic receptor polymorphisms and prevention of ventricular arrhythmias with bucindolol in patients with chronic heart failure. Circ Arrhythm Electrophysiol. 2013 Feb; 6(1):137-43.
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ß(1) Adrenergic receptor is key to cold- and diet-induced thermogenesis in mice. J Endocrinol. 2012 Sep; 214(3):359-65.
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A brighter side of ROS revealed by selective activation of beta-adrenergic receptor subtypes. J Physiol. 2010 Aug 15; 588(Pt 16):2973-4.