"Dexfenfluramine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The S-isomer of FENFLURAMINE. It is a serotonin agonist and is used as an anorectic. Unlike fenfluramine, it does not possess any catecholamine agonist activity.
| Descriptor ID |
D020372
|
| MeSH Number(s) |
D02.092.471.683.338
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Dexfenfluramine".
Below are MeSH descriptors whose meaning is more specific than "Dexfenfluramine".
This graph shows the total number of publications written about "Dexfenfluramine" by people in this website by year, and whether "Dexfenfluramine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 3 | 0 | 3 |
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Below are the most recent publications written about "Dexfenfluramine" by people in Profiles.
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Echocardiographic prevalence of mitral and/or aortic regurgitation in patients exposed to either fenfluramine-phentermine combination or to dexfenfluramine. Am J Cardiol. 1999 Dec 01; 84(11):1335-8.
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Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells. J Pharmacol Exp Ther. 1999 Dec; 291(3):1143-9.
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Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential. Am J Physiol. 1999 09; 277(3):L662-6.
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Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension. Am J Respir Crit Care Med. 1998 Oct; 158(4):1061-7.