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Sridevi Challa

TitleAssistant Professor
InstitutionUniversity of Chicago
DepartmentObstetrics and Gynecology-Gynecologic Oncology
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Challa S, Dasovich M, Abshier JC, Pekhale K, Yang L, Camacho CV, Kraus WL. PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells. J Biol Chem. 2026 Sep 08; 113540. PMID: 42710679.
      Citations:    
    2. Nguyen AQ, Bednarek N, Al-Sawalha I, Nagele B, Moroney F, Lastra JB, Myong S, Hosseinibarkooie S, Weng SHS, Kurnit KC, Yamada SD, Fleming GF, Challa S. Feedback activation of MAPK-ERK1/2 signaling causes resistance to trastuzumab-deruxtecan in endometrial cancers. Gynecol Oncol. 2026 Sep; 212:134-144. PMID: 42594534.
      Citations:    
    3. Rizo JA, Ahmad V, Pru JM, Winuthayanon S, Challa S, Kim TH, Jeong JW, Spencer TE, Kelleher AM. Uterine organoids reveal insights into epithelial specification and plasticity in development and disease. Proc Natl Acad Sci U S A. 2025 Feb 04; 122(5):e2422694122. PMID: 39883834; PMCID: PMC11804710.
      Citations: 4     Fields:    Translation:AnimalsCells
    4. Challa S, Nandu T, Kim HB, Gong X, Renshaw CW, Li WC, Tan X, Aljardali MW, Camacho CV, Chen J, Kraus WL. RACK1 MARylation regulates translation and stress granules in ovarian cancer cells. J Cell Biol. 2025 Feb 03; 224(2). PMID: 39760726; PMCID: PMC11702359.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    5. Spirtos AN, Aljardali MW, Challa S, Koul S, Lea JS, Kraus WL, Camacho CV. RBN-2397, a PARP7 Inhibitor, Synergizes with Paclitaxel to Inhibit Proliferation and Migration of Ovarian Cancer Cells. bioRxiv. 2024 Sep 05. PMID: 39229139; PMCID: PMC11370341.
      Citations:    
    6. Myong S, Nguyen AQ, Challa S. Biological Functions and Therapeutic Potential of NAD+ Metabolism in Gynecological Cancers. Cancers (Basel). 2024 Sep 05; 16(17). PMID: 39272943; PMCID: PMC11394644.
      Citations: 3     
    7. Challa S, Nandu T, Kim HB, Gong X, Renshaw CW, Li WC, Tan X, Aljardali MW, Camacho CV, Chen J, Kraus WL. A PARP14/TARG1-Regulated RACK1 MARylation Cycle Drives Stress Granule Dynamics in Ovarian Cancer Cells. bioRxiv. 2024 Sep 04. PMID: 37873085; PMCID: PMC10592810.
      Citations:    
    8. Challa S, Whitaker AL, Kraus WL. Detecting Poly (ADP-Ribose) In Vitro and in Cells Using PAR Trackers. Methods Mol Biol. 2023; 2609:75-90. PMID: 36515830.
      Citations: 1     Fields:    Translation:Cells
    9. Challa S, Ryu KW, Whitaker AL, Abshier JC, Camacho CV, Kraus WL. Development and characterization of new tools for detecting poly(ADP-ribose) in vitro and in vivo. Elife. 2022 04 27; 11. PMID: 35476036; PMCID: PMC9045816.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    10. Challa S, Kraus WL. Two birds, one stone: Non-canonical therapeutic effects of the PARP inhibitor Talazoparib. Cell Chem Biol. 2022 02 17; 29(2):171-173. PMID: 35180430.
      Citations: 4     Fields:    Translation:Humans
    11. Challa S, Khulpateea BR, Nandu T, Camacho CV, Ryu KW, Chen H, Peng Y, Lea JS, Kraus WL. Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers. Cell. 2021 08 19; 184(17):4531-4546.e26. PMID: 34314702; PMCID: PMC8380725.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    12. Challa S, Stokes MS, Kraus WL. MARTs and MARylation in the Cytosol: Biological Functions, Mechanisms of Action, and Therapeutic Potential. Cells. 2021 02 03; 10(2). PMID: 33546365; PMCID: PMC7913519.
      Citations: 37     Fields:    Translation:HumansCells
    13. Palavalli Parsons LH, Challa S, Gibson BA, Nandu T, Stokes MS, Huang D, Lea JS, Kraus WL. Identification of PARP-7 substrates reveals a role for MARylation in microtubule control in ovarian cancer cells. Elife. 2021 01 21; 10. PMID: 33475085; PMCID: PMC7884071.
      Citations: 45     Fields:    Translation:HumansCells
    14. Kim DS, Challa S, Jones A, Kraus WL. PARPs and ADP-ribosylation in RNA biology: from RNA expression and processing to protein translation and proteostasis. Genes Dev. 2020 03 01; 34(5-6):302-320. PMID: 32029452; PMCID: PMC7050490.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    15. Kim DS, Camacho CV, Nagari A, Malladi VS, Challa S, Kraus WL. Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21. Mol Cell. 2019 09 19; 75(6):1270-1285.e14. PMID: 31351877; PMCID: PMC6754283.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    16. Ryu KW, Nandu T, Kim J, Challa S, DeBerardinis RJ, Kraus WL. Metabolic regulation of transcription through compartmentalized NAD+ biosynthesis. Science. 2018 05 11; 360(6389). PMID: 29748257; PMCID: PMC6465534.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
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