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Chuan He to 5-Methylcytosine

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This is a "connection" page, showing publications Chuan He has written about 5-Methylcytosine.
Chuan He
Connection Strength
9.767
5-Methylcytosine
  1. Ultra-mild bisulfite outperforms existing methods for 5-methylcytosine detection with low input DNA. Nat Commun. 2025 Nov 13; 16(1):9939.
    View in: PubMed
    Score: 0.837
  2. RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis. Nature. 2024 10; 634(8035):986-994.
    View in: PubMed
    Score: 0.775
  3. Ultrafast bisulfite sequencing detection of 5-methylcytosine in DNA and RNA. Nat Biotechnol. 2024 Oct; 42(10):1559-1570.
    View in: PubMed
    Score: 0.735
  4. A human tissue map of 5-hydroxymethylcytosines exhibits tissue specificity through gene and enhancer modulation. Nat Commun. 2020 12 02; 11(1):6161.
    View in: PubMed
    Score: 0.594
  5. DNA 5-Methylcytosine-Specific Amplification and Sequencing. J Am Chem Soc. 2020 03 11; 142(10):4539-4543.
    View in: PubMed
    Score: 0.563
  6. Jump-seq: Genome-Wide Capture and Amplification of 5-Hydroxymethylcytosine Sites. J Am Chem Soc. 2019 06 05; 141(22):8694-8697.
    View in: PubMed
    Score: 0.534
  7. Tet-Assisted Bisulfite Sequencing (TAB-seq). Methods Mol Biol. 2018; 1708:645-663.
    View in: PubMed
    Score: 0.485
  8. A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations. Mol Cell. 2016 08 18; 63(4):711-719.
    View in: PubMed
    Score: 0.439
  9. A TET homologue protein from Coprinopsis cinerea (CcTET) that biochemically converts 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine. J Am Chem Soc. 2014 Apr 02; 136(13):4801-4.
    View in: PubMed
    Score: 0.373
  10. Potential functional roles of DNA demethylation intermediates. Trends Biochem Sci. 2013 Oct; 38(10):480-4.
    View in: PubMed
    Score: 0.358
  11. Tet-mediated covalent labelling of 5-methylcytosine for its genome-wide detection and sequencing. Nat Commun. 2013; 4:1517.
    View in: PubMed
    Score: 0.343
  12. Prognostic Significance of Cell-Free DNA Derived 5-Hydroxymethylcytosine Signatures in Newly Diagnosed Multiple Myeloma. JCO Precis Oncol. 2026 Jul; 10(7):e2501121.
    View in: PubMed
    Score: 0.219
  13. DMN-seq enriches DNA hypomethylated regions for biomarker discovery using 5-methylcytosine glycosylase. Genome Biol. 2026 Feb 11; 27(1).
    View in: PubMed
    Score: 0.213
  14. Brain-derived 5-hydroxymethylcytosine epigenetic scores are related to Alzheimer's disease pathology and cognitive decline. Acta Neuropathol. 2025 Oct 28; 150(1):45.
    View in: PubMed
    Score: 0.209
  15. Bisulfite Sequencing to Map 5-Methylcytosine Sites in Human Respiratory Syncytial Virus RNA. Methods Mol Biol. 2025; 2948:233-247.
    View in: PubMed
    Score: 0.197
  16. 5-Hydroxymethylated Biomarkers in Cell-Free DNA Predict Occult Colorectal Cancer up to 36 Months Before Diagnosis in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. JCO Precis Oncol. 2024 10; 8:e2400277.
    View in: PubMed
    Score: 0.194
  17. 5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer. Gynecol Oncol. 2024 03; 182:82-90.
    View in: PubMed
    Score: 0.185
  18. 5-Hydroxymethylcytosine Profiling of Cell-Free DNA Identifies Bivalent Genes That Are Prognostic of Survival in High-Risk Neuroblastoma. JCO Precis Oncol. 2024 01; 8:e2300297.
    View in: PubMed
    Score: 0.184
  19. PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023.
    View in: PubMed
    Score: 0.177
  20. PETCH-DB: a Portal for Exploring Tissue-specific and Complex disease-associated 5-Hydroxymethylcytosines. Database (Oxford). 2023 06 10; 2023.
    View in: PubMed
    Score: 0.177
  21. 5-Hydroxymethylcytosine Profiles in Circulating Cell-Free DNA Associate with Disease Burden in Children with Neuroblastoma. Clin Cancer Res. 2020 03 15; 26(6):1309-1317.
    View in: PubMed
    Score: 0.139
  22. Prognostic implications of 5-hydroxymethylcytosines from circulating cell-free DNA in diffuse large B-cell lymphoma. Blood Adv. 2019 10 08; 3(19):2790-2799.
    View in: PubMed
    Score: 0.137
  23. 5-Hydroxymethylcytosines in Circulating Cell-Free DNA Reveal Vascular Complications of Type 2 Diabetes. Clin Chem. 2019 11; 65(11):1414-1425.
    View in: PubMed
    Score: 0.137
  24. Post-transcriptional gene regulation by mRNA modifications. Nat Rev Mol Cell Biol. 2017 01; 18(1):31-42.
    View in: PubMed
    Score: 0.112
  25. DNA cytosine hydroxymethylation levels are distinct among non-overlapping classes of peripheral blood leukocytes. J Immunol Methods. 2016 09; 436:1-15.
    View in: PubMed
    Score: 0.108
  26. Nucleic Acid Modifications in Regulation of Gene Expression. Cell Chem Biol. 2016 Jan 21; 23(1):74-85.
    View in: PubMed
    Score: 0.106
  27. N6-methyldeoxyadenosine marks active transcription start sites in Chlamydomonas. Cell. 2015 May 07; 161(4):879-892.
    View in: PubMed
    Score: 0.101
  28. Nonenzymatic labeling of 5-hydroxymethylcytosine in nanopore sequencing. Chembiochem. 2013 Jul 22; 14(11):1289-90.
    View in: PubMed
    Score: 0.089
  29. Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell. 2013 Apr 25; 153(3):678-91.
    View in: PubMed
    Score: 0.088
  30. Tet-assisted bisulfite sequencing of 5-hydroxymethylcytosine. Nat Protoc. 2012 Dec; 7(12):2159-70.
    View in: PubMed
    Score: 0.085
  31. Nucleic acid modifications with epigenetic significance. Curr Opin Chem Biol. 2012 Dec; 16(5-6):516-24.
    View in: PubMed
    Score: 0.085
  32. Base-resolution analysis of 5-hydroxymethylcytosine in the mammalian genome. Cell. 2012 Jun 08; 149(6):1368-80.
    View in: PubMed
    Score: 0.082
  33. Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA. Org Lett. 2011 Jul 01; 13(13):3446-9.
    View in: PubMed
    Score: 0.077
  34. Detection of 5-hydroxymethylcytosine in DNA by transferring a keto-glucose by using T4 phage ß-glucosyltransferase. Chembiochem. 2011 Jul 25; 12(11):1682-5.
    View in: PubMed
    Score: 0.077
  35. Bioorthogonal labeling of 5-hydroxymethylcytosine in genomic DNA and diazirine-based DNA photo-cross-linking probes. Acc Chem Res. 2011 Sep 20; 44(9):709-17.
    View in: PubMed
    Score: 0.076
  36. Syntheses of two 5-hydroxymethyl-2'-deoxycytidine phosphoramidites with TBDMS as the 5-hydroxymethyl protecting group and their incorporation into DNA. J Org Chem. 2011 May 20; 76(10):4182-8.
    View in: PubMed
    Score: 0.076
  37. Detection of 5-hydroxymethylcytosine in a combined glycosylation restriction analysis (CGRA) using restriction enzyme Taq(a)I. Bioorg Med Chem Lett. 2011 Sep 01; 21(17):5075-7.
    View in: PubMed
    Score: 0.076
  38. Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine. Nat Biotechnol. 2011 Jan; 29(1):68-72.
    View in: PubMed
    Score: 0.074
  39. Hypoxia Promotes an Adrenergic to Mesenchymal Transcriptional Program Transition in Neuroblastoma. Clin Transl Sci. 2026 03; 19(3):e70508.
    View in: PubMed
    Score: 0.053
  40. Genome-Wide Mapping Implicates 5-Hydroxymethylcytosines in Diabetes Mellitus and Alzheimer's Disease. J Alzheimers Dis. 2023; 93(3):1135-1151.
    View in: PubMed
    Score: 0.043
  41. Genome-wide profiling of 5-hydroxymethylcytosines in circulating cell-free DNA reveals population-specific pathways in the development of multiple myeloma. J Hematol Oncol. 2022 08 16; 15(1):106.
    View in: PubMed
    Score: 0.042
  42. Base-resolution detection of N4-methylcytosine in genomic DNA using 4mC-Tet-assisted-bisulfite- sequencing. Nucleic Acids Res. 2015 Dec 02; 43(21):e148.
    View in: PubMed
    Score: 0.026
  43. 5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation. Mol Cell. 2014 Oct 23; 56(2):286-297.
    View in: PubMed
    Score: 0.024
  44. Hydroxymethylation at gene regulatory regions directs stem/early progenitor cell commitment during erythropoiesis. Cell Rep. 2014 Jan 16; 6(1):231-244.
    View in: PubMed
    Score: 0.023
  45. TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11994-9.
    View in: PubMed
    Score: 0.022
  46. Sensitive and specific single-molecule sequencing of 5-hydroxymethylcytosine. Nat Methods. 2011 Nov 20; 9(1):75-7.
    View in: PubMed
    Score: 0.020
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The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.