"V(D)J Recombination" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which the V (variable), D (diversity), and J (joining) segments of IMMUNOGLOBULIN GENES or T-CELL RECEPTOR GENES are assembled during the development of LYMPHOID CELLS using NONHOMOLOGOUS DNA END-JOINING.
| Descriptor ID |
D060152
|
| MeSH Number(s) |
G05.344.900 G05.728.932
|
| Concept/Terms |
V(D)J Recombination- V(D)J Recombination
- VDJ Recombination
- Recombination, VDJ
- Recombinations, VDJ
- VDJ Recombinations
|
Below are MeSH descriptors whose meaning is more general than "V(D)J Recombination".
Below are MeSH descriptors whose meaning is more specific than "V(D)J Recombination".
This graph shows the total number of publications written about "V(D)J Recombination" by people in this website by year, and whether "V(D)J Recombination" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "V(D)J Recombination" by people in Profiles.
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The endogenous Mtv8 locus and the immunoglobulin repertoire. Front Immunol. 2024; 15:1345467.
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Transcriptional programming and T cell receptor repertoires distinguish human lung and lymph node memory T cells. Commun Biol. 2019; 2:411.
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Transcription factories in Ig? allelic choice and diversity. Adv Immunol. 2019; 141:33-49.
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A new twist on V(D)J recombination. Nat Struct Mol Biol. 2018 08; 25(8):648-649.
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RAG Represents a Widespread Threat to the Lymphocyte Genome. Cell. 2015 Aug 13; 162(4):751-65.
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Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination. J Immunol. 2015 Mar 01; 194(5):2380-9.
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Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. J Exp Med. 2012 May 07; 209(5):955-63.