"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
| Descriptor ID |
D054439
|
| MeSH Number(s) |
D06.472.699.301 D12.644.548.322
|
| Concept/Terms |
GHRL Protein- GHRL Protein
- Ppghrelin
- Ghrelin-Obestatin Preprohormone
- Ghrelin Obestatin Preprohormone
- Motilin-Related Peptide Precursor
- Motilin Related Peptide Precursor
- Peptide Precursor, Motilin-Related
- Precursor, Motilin-Related Peptide
- PpMTLRP
- Ghrelin Precursor
- Precursor, Ghrelin
Appetite-Regulating Hormone- Appetite-Regulating Hormone
- Appetite Regulating Hormone
- Motilin-Related Peptide
- Motilin Related Peptide
- Gastric MLTRP
|
Below are MeSH descriptors whose meaning is more general than "Ghrelin".
Below are MeSH descriptors whose meaning is more specific than "Ghrelin".
This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ghrelin" by people in Profiles.
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Duration-sensitive association between air pollution exposure and changes in cardiometabolic biomarkers: Evidence from a predominantly African American cohort. Environ Res. 2024 Jan 01; 240(Pt 2):117496.
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Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity. Cell Metab. 2022 10 04; 34(10):1486-1498.e7.
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A Role for Hypocretin/Orexin in Metabolic and Sleep Abnormalities in a Mouse Model of Non-metastatic Breast Cancer. Cell Metab. 2018 Jul 03; 28(1):118-129.e5.
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LEAP2 Is an Endogenous Antagonist of the Ghrelin Receptor. Cell Metab. 2018 02 06; 27(2):461-469.e6.
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Loss of Action via Neurotensin-Leptin Receptor Neurons Disrupts Leptin and Ghrelin-Mediated Control of Energy Balance. Endocrinology. 2017 05 01; 158(5):1271-1288.
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Elevated ghrelin predicts food intake during experimental sleep restriction. Obesity (Silver Spring). 2016 Jan; 24(1):132-8.
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Chronic Electrical Stimulation at Acupoints Reduces Body Weight and Improves Blood Glucose in Obese Rats via Autonomic Pathway. Obes Surg. 2015 Jul; 25(7):1209-16.
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Circadian rhythm of circulating levels of the endocannabinoid 2-arachidonoylglycerol. J Clin Endocrinol Metab. 2015 Jan; 100(1):220-6.
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Characterization of a far-red analog of ghrelin for imaging GHS-R in P19-derived cardiomyocytes. Peptides. 2014 Apr; 54:81-8.
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Possible risk factors for increased suicide following bariatric surgery. Obesity (Silver Spring). 2013 Apr; 21(4):665-72.