"Adrenomedullin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.
| Descriptor ID |
D053607
|
| MeSH Number(s) |
D06.472.699.077 D12.644.548.017
|
| Concept/Terms |
PAMP(1-20)NH2- PAMP(1-20)NH2
- Proadrenomedullin N-Terminal 20 Peptide
- Proadrenomedullin N Terminal 20 Peptide
- Proadrenomedullin (1-20)
|
Below are MeSH descriptors whose meaning is more general than "Adrenomedullin".
Below are MeSH descriptors whose meaning is more specific than "Adrenomedullin".
This graph shows the total number of publications written about "Adrenomedullin" by people in this website by year, and whether "Adrenomedullin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Adrenomedullin" by people in Profiles.
-
Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 01; 304(11):L757-64.
-
Therapeutic targets in pulmonary arterial hypertension. Pharmacol Ther. 2009 Jan; 121(1):69-88.
-
The neuroprotective and vasculo-neuro-regenerative roles of adrenomedullin in ischemic brain and its therapeutic potential. Endocrinology. 2006 Apr; 147(4):1642-53.
-
Adrenomedullin provokes endothelial Akt activation and promotes vascular regeneration both in vitro and in vivo. FEBS Lett. 2003 Jun 05; 544(1-3):86-92.
-
Adrenomedullin promotes proliferation and migration of cultured endothelial cells. Hypertens Res. 2003 Feb; 26 Suppl:S93-8.
-
Increased pericardial fluid concentrations of the mature form of adrenomedullin in patients with cardiac remodelling. Heart. 2002 Mar; 87(3):242-6.
-
Oxidative stress augments secretion of endothelium-derived relaxing peptides, C-type natriuretic peptide and adrenomedullin. J Hypertens. 2000 May; 18(5):575-80.