"ELAV-Like Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RRM protein that binds to the 3'-UTR region of mRNAs and increases their stability. In EMBRYONIC STEM CELLS, it binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs and preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), to stabilize them and promote differentiation.
| Descriptor ID |
D000067780
|
| MeSH Number(s) |
D12.776.157.725.813.500.250 D12.776.664.962.813.500.250
|
| Concept/Terms |
ELAV-Like Protein 1- ELAV-Like Protein 1
- ELAV Like Protein 1
- HuR Paraneoplastic Encephalomyelitis Antigen
- HuR Protein
- Protein, HuR
- ELAVL1 protein
- protein, ELAVL1
- HuR Antigen
- Antigen, HuR
|
Below are MeSH descriptors whose meaning is more general than "ELAV-Like Protein 1".
Below are MeSH descriptors whose meaning is more specific than "ELAV-Like Protein 1".
This graph shows the total number of publications written about "ELAV-Like Protein 1" by people in this website by year, and whether "ELAV-Like Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "ELAV-Like Protein 1" by people in Profiles.
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HuR/ELAVL1 drives malignant peripheral nerve sheath tumor growth and metastasis. J Clin Invest. 2020 07 01; 130(7):3848-3864.
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Transgenic expression of HuR increases vasogenic edema and impedes functional recovery in rodent ischemic stroke. Neurosci Lett. 2017 Nov 20; 661:126-131.
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Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells. FASEB J. 2008 Aug; 22(8):2639-51.