"Ataxin-3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A deubiquitinating enzyme of the ATAXINS family. It functions in protein homeostasis, GENETIC TRANSCRIPTION; CYTOSKELETON regulation, and MYOGENESIS. CAG TRINUCLEOTIDE REPEAT EXPANSION in the Ataxin-3 gene coding region is associated with spinocerebellar ataxia-3 (MACHADO-JOSEPH DISEASE).
| Descriptor ID |
D000067699
|
| MeSH Number(s) |
D08.811.037.250 D12.776.631.069.875 D12.776.660.075.875
|
| Concept/Terms |
Ataxin-3- Ataxin-3
- Ataxin 3
- SCA3 Protein
- Ataxin-3 Protein
- Ataxin 3 Protein
- Machado-Joseph Disease Protein
- Machado Joseph Disease Protein
- Spinocerebellar Ataxia 3 Protein
- ATXN3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Ataxin-3".
Below are MeSH descriptors whose meaning is more specific than "Ataxin-3".
This graph shows the total number of publications written about "Ataxin-3" by people in this website by year, and whether "Ataxin-3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ataxin-3" by people in Profiles.
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Founder Effects of Spinocerebellar Ataxias in the American Continents and the Caribbean. Cerebellum. 2020 Jun; 19(3):446-458.
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The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex. Mol Endocrinol. 2013 Dec; 27(12):2105-15.
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French Machado-Joseph disease patients do not exhibit gametic segregation distortion: a sperm typing analysis. Hum Mol Genet. 1999 Sep; 8(9):1779-84.