Tartrate-Resistant Acid Phosphatase
"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
| Descriptor ID |
D000071681
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| MeSH Number(s) |
D08.811.277.352.650.025.500 D08.811.277.352.650.625.862
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| Concept/Terms |
Tartrate-Resistant Acid Phosphatase- Tartrate-Resistant Acid Phosphatase
- Acid Phosphatase, Tartrate-Resistant
- Phosphatase, Tartrate-Resistant Acid
- Tartrate Resistant Acid Phosphatase
- TRAcP
TRAP Type 5 AcPase- TRAP Type 5 AcPase
- Acid Phosphatase V
- Phosphatase V, Acid
- V, Acid Phosphatase
- AcPase V
- V, AcPase
- Type 5 Acid Phosphatase
- Tartrate-Resistant Acid Phosphatase Type 5
- Tartrate Resistant Acid Phosphatase Type 5
|
Below are MeSH descriptors whose meaning is more general than "Tartrate-Resistant Acid Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Tartrate-Resistant Acid Phosphatase".
This graph shows the total number of publications written about "Tartrate-Resistant Acid Phosphatase" by people in this website by year, and whether "Tartrate-Resistant Acid Phosphatase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tartrate-Resistant Acid Phosphatase" by people in Profiles.
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Combination therapy with BMP-2 and a systemic RANKL inhibitor enhances bone healing in a mouse critical-sized femoral defect. Bone. 2016 Mar; 84:93-103.
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ACP5 (Uteroferrin): phylogeny of an ancient and conserved gene expressed in the endometrium of mammals. Biol Reprod. 2012 Apr; 86(4):123.
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Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone. J Endocrinol. 2011 Nov; 211(2):145-56.
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Microarray analysis of the role of regional dura mater in cranial suture fate. Plast Reconstr Surg. 2008 Aug; 122(2):389-399.
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Beta2-microglobulin stimulates osteoclast formation. Kidney Int. 2008 Jun; 73(11):1275-81.
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Changes in location and number of tartrate-resistant acid phosphatase (TRAP)-positive cells during the development of type II collagen-induced arthritis in DBA/1J mice. Exp Anim. 1998 Jul; 47(3):211-4.