Pyruvate Dehydrogenase (Lipoamide)-Phosphatase
"Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
(Pyruvate dehydrogenase (lipoamide))-phosphate phosphohydrolase. A mitochondrial enzyme that catalyzes the hydrolytic removal of a phosphate on a specific seryl hydroxyl group of pyruvate dehydrogenase, reactivating the enzyme complex. EC 3.1.3.43.
Descriptor ID |
D011769
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MeSH Number(s) |
D08.811.277.352.650.625.725
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Concept/Terms |
Pyruvate Dehydrogenase (Lipoamide)-Phosphatase- Pyruvate Dehydrogenase (Lipoamide)-Phosphatase
- PDH Phosphatase
- Phosphatase, PDH
- Pyruvate Dehydrogenase Phosphatase
- Phosphatase, Pyruvate Dehydrogenase
- Pyruvate Dehydrogenase Phosphate Phosphatase
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Below are MeSH descriptors whose meaning is more general than "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase".
Below are MeSH descriptors whose meaning is more specific than "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase".
This graph shows the total number of publications written about "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" by people in this website by year, and whether "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pyruvate Dehydrogenase (Lipoamide)-Phosphatase" by people in Profiles.
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Tyr-94 phosphorylation inhibits pyruvate dehydrogenase phosphatase 1 and promotes tumor growth. J Biol Chem. 2014 Aug 01; 289(31):21413-22.
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Tyr phosphorylation of PDP1 toggles recruitment between ACAT1 and SIRT3 to regulate the pyruvate dehydrogenase complex. Mol Cell. 2014 Feb 20; 53(4):534-48.