"Apolipoprotein L1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ApoL protein highly expressed by the liver. It has anti-trypanosomal activity through its ability to permeabilize TRYPANOSOMA membranes. Mutations in the APOL1 gene are associated with type 4 FOCAL SEGMENTAL GLOMERULOSCLEROSIS .
| Descriptor ID |
D000075944
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| MeSH Number(s) |
D10.532.091.750.500 D12.776.070.400.750.500 D12.776.521.120.750.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Apolipoprotein L1".
Below are MeSH descriptors whose meaning is more specific than "Apolipoprotein L1".
This graph shows the total number of publications written about "Apolipoprotein L1" by people in this website by year, and whether "Apolipoprotein L1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2023 | 2 | 0 | 2 |
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Below are the most recent publications written about "Apolipoprotein L1" by people in Profiles.
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Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study. Elife. 2023 10 26; 12.
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APOL1 and the risk of adverse renal outcomes in patients of African ancestry with systemic lupus erythematosus. Lupus. 2023 May; 32(6):763-770.
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Effect of Sickle Cell Trait and APOL1 Genotype on the Association of Soluble uPAR with Kidney Function Measures in Black Americans. Clin J Am Soc Nephrol. 2021 Feb 08; 16(2):287-289.
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Hypertensive APOL1 risk allele carriers demonstrate greater blood pressure reduction with angiotensin receptor blockade compared to low risk carriers. PLoS One. 2019; 14(9):e0221957.
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Introducing Genetic Tests With Uncertain Implications in Living Donor Kidney Transplantation: ApoL1 as a Case Study. Prog Transplant. 2016 Sep; 26(3):203-6.
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Genetic association and gene-gene interaction analyses in African American dialysis patients with nondiabetic nephropathy. Am J Kidney Dis. 2012 Feb; 59(2):210-21.