Zonula Occludens-1 Protein
"Zonula Occludens-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 195-kDa zonula occludens protein with similarity to MEMBRANE-ASSOCIATED GUANYLATE KINASES. It is distinguished by the presence of a ZU5 domain at the C-terminal of the molecule.
| Descriptor ID |
D062826
|
| MeSH Number(s) |
D12.776.543.940.900.500
|
| Concept/Terms |
Zonula Occludens-1 Protein- Zonula Occludens-1 Protein
- Occludens-1 Protein, Zonula
- Zonula Occludens 1 Protein
- Tight Junction Protein ZO-1
- Tight Junction Protein ZO 1
- Zona Occludens 1 Protein
- Tight Junction Protein 1
|
Below are MeSH descriptors whose meaning is more general than "Zonula Occludens-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Zonula Occludens-1 Protein".
This graph shows the total number of publications written about "Zonula Occludens-1 Protein" by people in this website by year, and whether "Zonula Occludens-1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 8 | 8 |
| 2012 | 2 | 5 | 7 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2016 | 1 | 1 | 2 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 3 | 3 |
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Below are the most recent publications written about "Zonula Occludens-1 Protein" by people in Profiles.
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Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin a-helical bundle. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204618119.
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Confluence and tight junction dependence of volume regulation in epithelial tissue. Mol Biol Cell. 2022 09 15; 33(11):ar98.
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Tight junction proteins occludin and ZO-1 as regulators of epithelial proliferation and survival. Ann N Y Acad Sci. 2022 08; 1514(1):21-33.
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The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair. Gastroenterology. 2021 12; 161(6):1924-1939.
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ZO-1 Regulates Intercalated Disc Composition and Atrioventricular Node Conduction. Circ Res. 2020 07 03; 127(2):e28-e43.
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Idiopathic pulmonary fibrosis is associated with tight junction protein alterations. Biochim Biophys Acta Biomembr. 2020 05 01; 1862(5):183205.
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Inflammation-induced Occludin Downregulation Limits Epithelial Apoptosis by Suppressing Caspase-3 Expression. Gastroenterology. 2019 11; 157(5):1323-1337.
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Claudin-1-Dependent Destabilization of the Blood-Brain Barrier in Chronic Stroke. J Neurosci. 2019 01 23; 39(4):743-757.
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The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo. J Biol Chem. 2018 11 09; 293(45):17317-17335.
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Role of intestinal Hsp70 in barrier maintenance: contribution of milk to the induction of Hsp70.2. Pediatr Surg Int. 2018 Mar; 34(3):323-330.