Spike Glycoprotein, Coronavirus
"Spike Glycoprotein, Coronavirus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.
| Descriptor ID |
D064370
|
| MeSH Number(s) |
D12.776.543.512.500.665 D12.776.964.970.880.910.665
|
| Concept/Terms |
Spike Glycoprotein, Coronavirus- Spike Glycoprotein, Coronavirus
- Coronavirus Spike Glycoprotein
- Spike Protein, Coronavirus
- Coronavirus Spike Protein
- Glycoprotein S, Coronavirus
- Spike Glycoproteins, Coronavirus
|
Below are MeSH descriptors whose meaning is more general than "Spike Glycoprotein, Coronavirus".
Below are MeSH descriptors whose meaning is more specific than "Spike Glycoprotein, Coronavirus".
This graph shows the total number of publications written about "Spike Glycoprotein, Coronavirus" by people in this website by year, and whether "Spike Glycoprotein, Coronavirus" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 3 | 4 |
| 2021 | 4 | 14 | 18 |
| 2022 | 1 | 10 | 11 |
| 2024 | 2 | 3 | 5 |
| 2025 | 1 | 4 | 5 |
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Below are the most recent publications written about "Spike Glycoprotein, Coronavirus" by people in Profiles.
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HLA-B*15:01-positive severe COVID-19 patients lack CD8+ T cell pools with highly expanded public clonotypes. Proc Natl Acad Sci U S A. 2025 Sep 09; 122(36):e2503145122.
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Genetic markers of enhanced functional antibody responses to COVID-19 vaccination. Vaccine. 2025 Aug 13; 61:127379.
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SARS-CoV-2 ORF3a drives dynamic dense body formation for optimal viral infectivity. Nat Commun. 2025 May 12; 16(1):4393.
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Using SARS-CoV-2 red cell kodecytes to assess vaccine-induced immune response to the conserved 1147-58 region of the spike protein in Indian blood donors: exploring the potential role of blood transfusion services in population surveillance. Transfus Clin Biol. 2025 Aug; 32(3):286-291.
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Neutralizing antibody immune correlates in COVAIL trial recipients of an mRNA second COVID-19 vaccine boost. Nat Commun. 2025 Jan 17; 16(1):759.
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Mucosal vaccination against SARS-CoV-2 using recombinant influenza viruses delivering self-assembling nanoparticles. Vaccine. 2025 02 06; 46:126668.
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SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years. Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39):e2411428121.
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Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunity. Nat Commun. 2024 May 16; 15(1):4177.
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Marine sulfated glycans inhibit the interaction of heparin with S-protein of SARS-CoV-2 Omicron XBB variant. Glycoconj J. 2024 04; 41(2):163-174.
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Comparing population-level humoral and cellular immunity to SARS-Cov-2 in Bangalore, India. Sci Rep. 2024 03 08; 14(1):5758.