Receptor, Metabotropic Glutamate 5
"Receptor, Metabotropic Glutamate 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A type I G protein-coupled receptor mostly expressed post-synaptic pyramidal cells of the cortex and CENTRAL NERVOUS SYSTEM.
| Descriptor ID |
D064529
|
| MeSH Number(s) |
D12.776.543.750.695.450.500 D12.776.543.750.720.200.450.500.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Metabotropic Glutamate 5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Metabotropic Glutamate [D12.776.543.750.695.450]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.695.450.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Amino Acid [D12.776.543.750.720.200]
- Receptors, Glutamate [D12.776.543.750.720.200.450]
- Receptors, Metabotropic Glutamate [D12.776.543.750.720.200.450.500]
- Receptor, Metabotropic Glutamate 5 [D12.776.543.750.720.200.450.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Metabotropic Glutamate 5".
This graph shows the total number of publications written about "Receptor, Metabotropic Glutamate 5" by people in this website by year, and whether "Receptor, Metabotropic Glutamate 5" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Metabotropic Glutamate 5" by people in Profiles.
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Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [18F]FPEB and positron emission tomography study in rats. Neuropsychopharmacology. 2023 02; 48(3):489-497.
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The metabotropic glutamate receptor 5 negative allosteric modulator fenobam: pharmacokinetics, side effects, and analgesic effects in healthy human subjects. Pain. 2020 01; 161(1):135-146.
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Alteration in 5-HT2C, NMDA receptor and IP3 in cerebral cortex of epileptic rats: restorative role of Bacopa monnieri. Neurochem Res. 2015 Jan; 40(1):216-25.
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Metabotropic glutamate receptors (mGluR5) activate transient receptor potential canonical channels to improve the regularity of the respiratory rhythm generated by the pre-Bötzinger complex in mice. Eur J Neurosci. 2012 Jun; 35(11):1725-37.
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Metabotropic glutamate receptor 5 antagonism with fenobam: examination of analgesic tolerance and side effect profile in mice. Anesthesiology. 2011 Dec; 115(6):1239-50.
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Glutamate and NMDA receptors activation leads to cerebellar dysfunction and impaired motor coordination in unilateral 6-hydroxydopamine lesioned Parkinson's rat: functional recovery with bone marrow cells, serotonin and GABA. Mol Cell Biochem. 2011 Jul; 353(1-2):47-57.
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Endocannabinoid- and mGluR5-dependent short-term synaptic depression in an isolated neuron/bouton preparation from the hippocampal CA1 region. J Neurophysiol. 2008 Aug; 100(2):1041-52.
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Differential roles of hippocampal metabotropic glutamate receptors 1 and 5 in inhibitory avoidance learning. Neurobiol Learn Mem. 2007 Oct; 88(3):305-11.
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Refined linkage to the RDP/DYT12 locus on 19q13.2 and evaluation of GRIK5 as a candidate gene. Mov Disord. 2004 Jul; 19(7):845-847.
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Assessment of a prepulse inhibition deficit in a mutant mouse lacking mGlu5 receptors. Mol Psychiatry. 2004 Jan; 9(1):35-41.