Solute Carrier Family 12, Member 2
"Solute Carrier Family 12, Member 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Na-K-Cl transporter ubiquitously expressed. It plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells.
| Descriptor ID |
D064506
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| MeSH Number(s) |
D12.776.157.530.450.625.750.625 D12.776.157.530.937.750.625 D12.776.543.585.450.625.750.625 D12.776.543.585.937.875.625
|
| Concept/Terms |
Solute Carrier Family 12, Member 2- Solute Carrier Family 12, Member 2
- Bumetanide-Sensitive Sodium Potassium Chloride Cotransporter 2
- Bumetanide Sensitive Sodium Potassium Chloride Cotransporter 2
- Sodium-Potassium-Chloride Cotransporter 1 Protein
- Sodium Potassium Chloride Cotransporter 1 Protein
- BSC2 Protein
- Protein, BSC2
- BSC2 Transport Protein
- Protein, BSC2 Transport
- Transport Protein, BSC2
- Bumetanide-Sensitive Cotransporter 2
- Bumetanide Sensitive Cotransporter 2
- Cotransporter 2, Bumetanide-Sensitive
- NKCC1 Protein
- Protein, NKCC1
- SLC12A2 Cotransporter
- Cotransporter, SLC12A2
- Solute Carrier Family 12 (Sodium Potassium Chloride Transporters), Member 2
- SLC12A2 Protein
- Protein, SLC12A2
- SLC12A2 Transporter
- Transporter, SLC12A2
- NKCC1 Cotransporter
- Cotransporter, NKCC1
- NKCC1 Transport Protein
- Protein, NKCC1 Transport
- Transport Protein, NKCC1
|
Below are MeSH descriptors whose meaning is more general than "Solute Carrier Family 12, Member 2".
Below are MeSH descriptors whose meaning is more specific than "Solute Carrier Family 12, Member 2".
This graph shows the total number of publications written about "Solute Carrier Family 12, Member 2" by people in this website by year, and whether "Solute Carrier Family 12, Member 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Solute Carrier Family 12, Member 2" by people in Profiles.
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Role of environmental stressors in determining the developmental outcome of neonatal anesthesia. Psychoneuroendocrinology. 2017 Jul; 81:96-104.
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Capsaicin induces NKCC1 internalization and inhibits chloride secretion in colonic epithelial cells independently of TRPV1. Am J Physiol Gastrointest Liver Physiol. 2013 Jan 15; 304(2):G142-56.
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Activated PKC{delta} and PKC{epsilon} inhibit epithelial chloride secretion response to cAMP via inducing internalization of the Na+-K+-2Cl- cotransporter NKCC1. J Biol Chem. 2010 Oct 29; 285(44):34072-85.
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Phorbol 12-myristate 13-acetate-induced endocytosis of the Na-K-2Cl cotransporter in MDCK cells is associated with a clathrin-dependent pathway. Am J Physiol Cell Physiol. 2010 Jan; 298(1):C85-97.
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Ammonium transport in the colonic crypt cell line, T84: role for Rhesus glycoproteins and NKCC1. Am J Physiol Gastrointest Liver Physiol. 2008 Feb; 294(2):G429-40.
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Cell-volume-dependent vascular smooth muscle contraction: role of Na+, K+, 2Cl- cotransport, intracellular Cl- and L-type Ca2+ channels. Pflugers Arch. 2004 Oct; 449(1):42-55.
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WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia. Proc Natl Acad Sci U S A. 2004 Feb 17; 101(7):2064-9.
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Stabilization of beta-catenin induces lesions reminiscent of prostatic intraepithelial neoplasia, but terminal squamous transdifferentiation of other secretory epithelia. Oncogene. 2002 Jun 13; 21(26):4099-107.
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Molecular regulation of Na+-K+-2Cl- cotransporter (NKCC1) and epithelial chloride secretion. World J Surg. 2002 Jul; 26(7):826-30.