"Digitonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoside obtained from Digitalis purpurea; the aglycone is digitogenin which is bound to five sugars. Digitonin solubilizes lipids, especially in membranes and is used as a tool in cellular biochemistry, and reagent for precipitating cholesterol. It has no cardiac effects.
| Descriptor ID |
D004072
|
| MeSH Number(s) |
D04.210.500.155.580.130.500.236 D09.408.180.261.236
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Digitonin".
Below are MeSH descriptors whose meaning is more specific than "Digitonin".
This graph shows the total number of publications written about "Digitonin" by people in this website by year, and whether "Digitonin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Digitonin" by people in Profiles.
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Detergent wash improves vaccinated lymph node handling ex vivo. J Immunol Methods. 2021 02; 489:112943.
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Mouse chromaffin cells have two populations of dense core vesicles. J Neurophysiol. 2005 Sep; 94(3):2093-104.
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Distinct subcellular localization of transiently expressed types 1 and 2 iodothyronine deiodinases as determined by immunofluorescence confocal microscopy. Endocrinology. 2000 Nov; 141(11):4309-12.
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Type III machines of pathogenic yersiniae secrete virulence factors into the extracellular milieu. Mol Microbiol. 1999 Mar; 31(6):1619-29.
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Targeting of Yersinia Yop proteins into the cytosol of HeLa cells: one-step translocation of YopE across bacterial and eukaryotic membranes is dependent on SycE chaperone. Mol Microbiol. 1998 May; 28(3):593-601.
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Import of transcription factor MTF1 into the yeast mitochondria takes place through an unusual pathway. J Biol Chem. 1995 May 19; 270(20):11970-6.
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Fusion proteins containing the cytochrome b2 presequence are sorted to the mitochondrial intermembrane space independently of hsp60. J Biol Chem. 1994 Jun 24; 269(25):17279-88.
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Endosomes are acidified by association with discrete proton-pumping vacuoles in Dictyostelium. J Biol Chem. 1991 Mar 25; 266(9):5514-20.
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Solubilization and partial purification of hyaluronate synthetase from oligodendroglioma cells. J Biol Chem. 1989 Jul 15; 264(20):11776-83.
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Calcium mobilization in permeabilized fibroblasts: effects of inositol trisphosphate, orthovanadate, mitogens, phorbol ester, and guanosine triphosphate. J Cell Physiol. 1987 Jan; 130(1):29-36.