"Misonidazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nitroimidazole that sensitizes normally radio-resistant hypoxic cells to radiation. It may also be directly cytotoxic to hypoxic cells and has been proposed as an antineoplastic.
| Descriptor ID |
D008920
|
| MeSH Number(s) |
D02.640.672.530 D03.383.129.308.658.530
|
| Concept/Terms |
Misonidazole- Misonidazole
- alpha-(Methoxymethyl)-2-nitro-1H-imidazole-1-ethanol
Ro 07-0582- Ro 07-0582
- Ro 07 0582
- Ro 070582
- Ro 7-0582
- Ro 7 0582
- Ro 70582
|
Below are MeSH descriptors whose meaning is more general than "Misonidazole".
Below are MeSH descriptors whose meaning is more specific than "Misonidazole".
This graph shows the total number of publications written about "Misonidazole" by people in this website by year, and whether "Misonidazole" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Misonidazole" by people in Profiles.
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The optimal 18F-fluoromisonidazole PET threshold to define tumor hypoxia in preclinical squamous cell carcinomas using pO2 electron paramagnetic resonance imaging as reference truth. Eur J Nucl Med Mol Imaging. 2022 Oct; 49(12):4014-4024.
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Improving Tumor Hypoxia Location in 18F-Misonidazole PET with Dynamic Contrast-enhanced MRI Using Quantitative Electron Paramagnetic Resonance Partial Oxygen Pressure Images. Radiol Imaging Cancer. 2021 03; 3(2):e200104.
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Molecular imaging of hypoxia. J Nucl Med. 2011 Feb; 52(2):165-8.
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Tumor sensitizing effect by misonidazole in a clinically relevant radiation dose range. Int J Radiat Oncol Biol Phys. 1984 Mar; 10(3):379-83.
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Lung tumorigenic response of strain A mice exposed to hypoxic cell sensitizers alone and in combination with gamma-radiation. Cancer Res. 1983 Jan; 43(1):146-9.
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Chemical modulation of the hypoxic fraction in the treatment of head and neck cancer. Ann Otol Rhinol Laryngol. 1982 Jul-Aug; 91(4 Pt 1):461-4.
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The effect of misonidazole in situ on the radiation response of selected tumor subpopoulations. Cancer Clin Trials. 1980; 3(2):149-54.