Membrane Cofactor Protein
"Membrane Cofactor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed complement receptor that binds COMPLEMENT C3B and COMPLEMENT C4B and serves as a co-factor for their inactivation by COMPLEMENT FACTOR I. It also interacts with a wide variety of pathogens and mediates the immune response.
| Descriptor ID |
D051916
|
| MeSH Number(s) |
D12.776.124.486.274.920.124 D12.776.543.750.705.833.124
|
| Concept/Terms |
Membrane Cofactor Protein- Membrane Cofactor Protein
- CD46 Antigens
- Antigens, CD46
- CD46 Antigen
- Antigen, CD46
- Trophoblast-Leukocyte Common Antigen
- Common Antigen, Trophoblast-Leukocyte
- Trophoblast Leukocyte Common Antigen
|
Below are MeSH descriptors whose meaning is more general than "Membrane Cofactor Protein".
Below are MeSH descriptors whose meaning is more specific than "Membrane Cofactor Protein".
This graph shows the total number of publications written about "Membrane Cofactor Protein" by people in this website by year, and whether "Membrane Cofactor Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 2 | 3 |
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Below are the most recent publications written about "Membrane Cofactor Protein" by people in Profiles.
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Synthetic liver function is detectable in transgenic porcine livers perfused with human blood. Xenotransplantation. 2018 01; 25(1).
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N-glycolylneuraminic acid knockout reduces erythrocyte sequestration and thromboxane elaboration in an ex vivo pig-to-human xenoperfusion model. Xenotransplantation. 2017 11; 24(6).
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Transgenic expression of human leukocyte antigen-E attenuates GalKO.hCD46 porcine lung xenograft injury. Xenotransplantation. 2017 03; 24(2).
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Early graft failure of GalTKO pig organs in baboons is reduced by expression of a human complement pathway-regulatory protein. Xenotransplantation. 2015 Jul-Aug; 22(4):310-6.
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Pig-to-baboon liver xenoperfusion utilizing GalTKO.hCD46 pigs and glycoprotein Ib blockade. Xenotransplantation. 2014 May-Jun; 21(3):274-86.
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Role of cellular heparan sulfate proteoglycans in infection of human adenovirus serotype 3 and 35. PLoS Pathog. 2008 Oct; 4(10):e1000189.
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Characterization of infectivity of knob-modified adenoviral vectors in glioma. Cancer Biol Ther. 2008 May; 7(5):786-93.
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CD46 represents a target for adenoviral gene therapy of malignant glioma. Hum Gene Ther. 2006 May; 17(5):556-64.
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Detection of partial and complete acrosome reaction in human spermatozoa: which inducers and probes to use? Mol Hum Reprod. 1999 Mar; 5(3):214-9.