Receptor, Anaphylatoxin C5a
"Receptor, Anaphylatoxin C5a" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A G-protein-coupled receptor that signals an increase in intracellular calcium in response to the potent ANAPHYLATOXIN peptide COMPLEMENT C5A.
| Descriptor ID |
D044087
|
| MeSH Number(s) |
D12.776.543.750.695.024 D12.776.543.750.705.833.550
|
| Concept/Terms |
Receptor, Anaphylatoxin C5a- Receptor, Anaphylatoxin C5a
- CD88 Antigen
- Antigen, CD88
- Receptor, Complement 5a
- CD88 Antigens
- Anaphylatoxin C5a Receptor
- Antigens, CD88
- C5a Receptors
- Receptors, C5a
- Complement 5a Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Anaphylatoxin C5a".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Anaphylatoxin C5a".
This graph shows the total number of publications written about "Receptor, Anaphylatoxin C5a" by people in this website by year, and whether "Receptor, Anaphylatoxin C5a" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 3 | 1 | 4 |
| 2016 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Anaphylatoxin C5a" by people in Profiles.
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Absence of complement factor H reduces physical performance in C57BL6 mice. Immunobiology. 2020 09; 225(5):152003.
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C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupus. Immunology. 2016 08; 148(4):407-19.
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Painting factor H onto mesenchymal stem cells protects the cells from complement- and neutrophil-mediated damage. Biomaterials. 2016 09; 102:209-19.
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Complement anaphylatoxin receptors C3aR and C5aR are required in the pathogenesis of experimental autoimmune uveitis. J Leukoc Biol. 2016 Mar; 99(3):447-54.
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C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology. 2015 Sep; 146(1):130-43.
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Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor. Cell Mol Immunol. 2016 09; 13(5):651-7.
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CD11b is protective in complement-mediated immune complex glomerulonephritis. Kidney Int. 2015 May; 87(5):930-9.
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Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1ß release. J Immunol. 2013 Aug 01; 191(3):1006-10.
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Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathog. 2013 Jan; 9(1):e1003115.
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The C5a receptor has a key role in immune complex glomerulonephritis in complement factor H-deficient mice. Kidney Int. 2012 Nov; 82(9):961-8.