"Off-Label Use" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of prescribing or using a drug outside the scope of the drug's official approved label as designated by a regulatory agency concerning the treatment of a particular disease or condition.
| Descriptor ID |
D056687
|
| MeSH Number(s) |
E02.319.307.500
|
| Concept/Terms |
Off-Label Use- Off-Label Use
- Off Label Use
- Off-Label Uses
- Use, Off-Label
- Uses, Off-Label
- Off-Label Prescribing
- Off Label Prescribing
- Off-Label Prescribings
- Prescribing, Off-Label
- Prescribings, Off-Label
- Unlabeled Indication
- Indication, Unlabeled
- Indications, Unlabeled
- Unlabeled Indications
|
Below are MeSH descriptors whose meaning is more general than "Off-Label Use".
Below are MeSH descriptors whose meaning is more specific than "Off-Label Use".
This graph shows the total number of publications written about "Off-Label Use" by people in this website by year, and whether "Off-Label Use" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Off-Label Use" by people in Profiles.
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Off-Label use of Woven EndoBridge device for intracranial brain aneurysm treatment: Modeling of occlusion outcome. J Stroke Cerebrovasc Dis. 2024 Nov; 33(11):107897.
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Concerns about SARS-CoV-2 evolution should not hold back efforts to expand vaccination. Nat Rev Immunol. 2021 05; 21(5):330-335.
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Memantine treatment of trichotillomania. Ann Clin Psychiatry. 2020 05 01; 32(2):144-145.
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Off-Label Use of the WEB Device. World Neurosurg. 2020 Feb; 134:e1047-e1052.
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Posterior Reversible Encephalopathy Syndrome Instigated by Off-Label Disulfiram Use for Metastatic Melanoma. Psychosomatics. 2020 May - Jun; 61(3):302-306.
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State insurance mandates and off-label use of chemotherapy. Health Econ. 2018 01; 27(1):e55-e70.
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Intended and Unintended Consequences of Constraining Clinician Prescribing: The Case of Antipsychotics. Crit Care Med. 2016 10; 44(10):1805-7.
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Survey of the Effectiveness of Internet Information on Patient Education for Bone Morphogenetic Protein. World Neurosurg. 2016 Mar; 87:613-8.
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Prevalence and Perioperative Outcomes of Off-Label Total Hip and Knee Arthroplasty in the United States, 2000-2010. J Arthroplasty. 2015 Nov; 30(11):1872-8.
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Improving evidence developed from population-level experience with targeted agents. Clin Pharmacol Ther. 2015 May; 97(5):478-87.