"Drug Substitution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The practice of replacing one prescribed drug with another that is expected to have the same clinical or psychological effect.
| Descriptor ID |
D057915
|
| MeSH Number(s) |
E02.319.307.312 N02.421.668.778.500.312
|
| Concept/Terms |
Drug Substitution- Drug Substitution
- Drug Substitutions
- Substitution, Drug
- Substitutions, Drug
- Therapeutic Substitution
- Substitution, Therapeutic
- Substitutions, Therapeutic
- Therapeutic Substitutions
- Drug Switching
- Drug Switchings
- Switching, Drug
- Switchings, Drug
Generic Substitution- Generic Substitution
- Generic Substitutions
- Substitution, Generic
- Substitutions, Generic
|
Below are MeSH descriptors whose meaning is more general than "Drug Substitution".
Below are MeSH descriptors whose meaning is more specific than "Drug Substitution".
This graph shows the total number of publications written about "Drug Substitution" by people in this website by year, and whether "Drug Substitution" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 3 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 3 | 5 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2024 | 0 | 3 | 3 |
| 2025 | 1 | 1 | 2 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Drug Substitution" by people in Profiles.
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High-Dose Buprenorphine Initiation to Rapidly Transition From High-Dose Methadone in the Hospital. Subst Use Addctn J. 2026 Jul; 47(3):917-922.
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The effect of switching antipsychotics to aripiprazole versus paliperidone on weight/cardiometabolic parameters: 18-month follow-up findings from the European Long-acting Antipsychotics in Schizophrenia Trial (EULAST). Eur Neuropsychopharmacol. 2026 01; 102:49-57.
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Efficacy, Safety, and Immunogenicity of SDZ-ADL, an Adalimumab Biosimilar, in Biologic-Naïve and Switched Patients with Immune-Mediated Inflammatory Diseases: A Literature Review. Adv Ther. 2025 Mar; 42(3):1360-1392.
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Real-World Persistence of Successive Biologics in Patients With Inflammatory Bowel Disease: Findings From ROTARY. Inflamm Bowel Dis. 2024 10 03; 30(10):1776-1787.
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Sequencing of Targeted Therapy in Psoriasis: Does it Matter? Am J Clin Dermatol. 2024 Sep; 25(5):795-810.
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Bivalirudin as a substitute for heparin in neurointervention for patients with heparin-induced thrombocytopenia. J Stroke Cerebrovasc Dis. 2024 Jun; 33(6):107310.
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Ambulatory Transition from Parenteral Prostanoid to Inhaled Treprostinil in Patients with Pulmonary Arterial Hypertension. Lung. 2020 02; 198(1):53-58.
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Outcome of elective switching to vedolizumab in inflammatory bowel disease patients under tumor necrosis factor antagonist-maintained clinical remission. J Gastroenterol Hepatol. 2019 Dec; 34(12):2090-2095.
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Warfarin in nonvalvular atrial fibrillation-Time for a change? Semin Dial. 2019 11; 32(6):520-526.
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Psoriasis Area and Severity Index response in moderate-severe psoriatic patients switched to adalimumab: results from the OPPSA study. J Eur Acad Dermatol Venereol. 2018 Oct; 32(10):1737-1744.