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Connection

Stephen Archer to Rats, Sprague-Dawley

This is a "connection" page, showing publications Stephen Archer has written about Rats, Sprague-Dawley.
Connection Strength

2.389
  1. Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis. Circ Res. 2020 06 05; 126(12):1723-1745.
    View in: PubMed
    Score: 0.148
  2. Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury. FASEB J. 2020 01; 34(1):1447-1464.
    View in: PubMed
    Score: 0.145
  3. Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities. Int J Mol Sci. 2018 Sep 12; 19(9).
    View in: PubMed
    Score: 0.133
  4. Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension. J Am Heart Assoc. 2017 May 31; 6(6).
    View in: PubMed
    Score: 0.122
  5. Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension. J Mol Med (Berl). 2017 04; 95(4):381-393.
    View in: PubMed
    Score: 0.120
  6. PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension. Am J Respir Crit Care Med. 2013 Apr 15; 187(8):865-78.
    View in: PubMed
    Score: 0.092
  7. GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension. Circulation. 2012 Dec 11; 126(24):2859-69.
    View in: PubMed
    Score: 0.089
  8. Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension. Circ Res. 2012 May 25; 110(11):1484-97.
    View in: PubMed
    Score: 0.086
  9. Lung ยน8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension. Am J Respir Crit Care Med. 2012 Mar 15; 185(6):670-9.
    View in: PubMed
    Score: 0.084
  10. Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle. J Mol Med (Berl). 2012 Jan; 90(1):31-43.
    View in: PubMed
    Score: 0.082
  11. A central role for CD68(+) macrophages in hepatopulmonary syndrome. Reversal by macrophage depletion. Am J Respir Crit Care Med. 2011 Apr 15; 183(8):1080-91.
    View in: PubMed
    Score: 0.078
  12. Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2010 Sep; 299(3):L401-12.
    View in: PubMed
    Score: 0.075
  13. Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target. Circulation. 2010 Jun 22; 121(24):2661-71.
    View in: PubMed
    Score: 0.075
  14. The inhibition of pyruvate dehydrogenase kinase improves impaired cardiac function and electrical remodeling in two models of right ventricular hypertrophy: resuscitating the hibernating right ventricle. J Mol Med (Berl). 2010 Jan; 88(1):47-60.
    View in: PubMed
    Score: 0.073
  15. Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. Am J Physiol Lung Cell Mol Physiol. 2007 Oct; 293(4):L933-40.
    View in: PubMed
    Score: 0.062
  16. Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2007 Apr; 292(4):L872-8.
    View in: PubMed
    Score: 0.059
  17. The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels. FASEB J. 2004 Sep; 18(12):1382-91.
    View in: PubMed
    Score: 0.050
  18. Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res. 2004 Aug 06; 95(3):308-18.
    View in: PubMed
    Score: 0.050
  19. Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding. Acta Physiol (Oxf). 2022 02; 234(2):e13764.
    View in: PubMed
    Score: 0.042
  20. Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels. Circulation. 2002 Jan 15; 105(2):244-50.
    View in: PubMed
    Score: 0.042
  21. Potassium channels regulate tone in rat pulmonary veins. Am J Physiol Lung Cell Mol Physiol. 2001 Jun; 280(6):L1138-47.
    View in: PubMed
    Score: 0.040
  22. Alterations in a redox oxygen sensing mechanism in chronic hypoxia. J Appl Physiol (1985). 2001 Jun; 90(6):2249-56.
    View in: PubMed
    Score: 0.040
  23. Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension. Int J Mol Sci. 2020 Oct 01; 21(19).
    View in: PubMed
    Score: 0.038
  24. Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion. Acta Physiol (Oxf). 2020 08; 229(4):e13483.
    View in: PubMed
    Score: 0.037
  25. Dexfenfluramine elevates systemic blood pressure by inhibiting potassium currents in vascular smooth muscle cells. J Pharmacol Exp Ther. 1999 Dec; 291(3):1143-9.
    View in: PubMed
    Score: 0.036
  26. Ndufs2, a Core Subunit of Mitochondrial Complex I, Is Essential for Acute Oxygen-Sensing and Hypoxic Pulmonary Vasoconstriction. Circ Res. 2019 06 07; 124(12):1727-1746.
    View in: PubMed
    Score: 0.035
  27. Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat. J Vis Exp. 2018 11 18; (141).
    View in: PubMed
    Score: 0.034
  28. Molecular identification of the role of voltage-gated K+ channels, Kv1.5 and Kv2.1, in hypoxic pulmonary vasoconstriction and control of resting membrane potential in rat pulmonary artery myocytes. J Clin Invest. 1998 Jun 01; 101(11):2319-30.
    View in: PubMed
    Score: 0.033
  29. Utility of a nitric oxide electrode for monitoring the administration of nitric oxide in biologic systems. J Lab Clin Med. 1998 Mar; 131(3):281-5.
    View in: PubMed
    Score: 0.032
  30. Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction. Circulation. 1996 Nov 01; 94(9):2216-20.
    View in: PubMed
    Score: 0.029
  31. Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis. Eur Respir J. 1996 Jul; 9(7):1475-81.
    View in: PubMed
    Score: 0.029
  32. Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension. Cardiovasc Res. 1996 Jan; 31(1):55-62.
    View in: PubMed
    Score: 0.028
  33. Activation of the cGMP-dependent protein kinase mimics the stimulatory effect of nitric oxide and cGMP on calcium-gated potassium channels. Physiol Res. 1995; 44(1):39-44.
    View in: PubMed
    Score: 0.026
  34. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7583-7.
    View in: PubMed
    Score: 0.025
  35. Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats. J Appl Physiol (1985). 1994 Feb; 76(2):933-40.
    View in: PubMed
    Score: 0.024
  36. NG-monomethyl-L-arginine causes nitric oxide synthesis in isolated arterial rings: trouble in paradise. Biochem Biophys Res Commun. 1992 Oct 30; 188(2):590-6.
    View in: PubMed
    Score: 0.022
  37. Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia. Circulation. 2011 May 17; 123(19):2120-31.
    View in: PubMed
    Score: 0.020
  38. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med. 2009 Dec 01; 180(11):1131-42.
    View in: PubMed
    Score: 0.018
  39. Phosphodiesterase type 5 is highly expressed in the hypertrophied human right ventricle, and acute inhibition of phosphodiesterase type 5 improves contractility. Circulation. 2007 Jul 17; 116(3):238-48.
    View in: PubMed
    Score: 0.015
  40. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Proc Natl Acad Sci U S A. 2007 Jul 03; 104(27):11418-23.
    View in: PubMed
    Score: 0.015
  41. An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension. Circulation. 2006 Jun 06; 113(22):2630-41.
    View in: PubMed
    Score: 0.014
  42. Pergolide is an inhibitor of voltage-gated potassium channels, including Kv1.5, and causes pulmonary vasoconstriction. Circulation. 2005 Sep 06; 112(10):1494-9.
    View in: PubMed
    Score: 0.014
  43. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest. 2005 Jun; 115(6):1479-91.
    View in: PubMed
    Score: 0.013
  44. In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats. Circulation. 2003 Apr 22; 107(15):2037-44.
    View in: PubMed
    Score: 0.011
  45. Dexfenfluramine increases pulmonary artery smooth muscle intracellular Ca2+, independent of membrane potential. Am J Physiol. 1999 09; 277(3):L662-6.
    View in: PubMed
    Score: 0.009
  46. Vitamin A decreases the incidence and severity of nitrofen-induced congenital diaphragmatic hernia in rats. Am J Physiol. 1999 08; 277(2):L423-9.
    View in: PubMed
    Score: 0.009
  47. Effects of fluoxetine, phentermine, and venlafaxine on pulmonary arterial pressure and electrophysiology. Am J Physiol. 1999 02; 276(2):L213-9.
    View in: PubMed
    Score: 0.009
  48. The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats. Proc Soc Exp Biol Med. 1996 Oct; 213(1):43-9.
    View in: PubMed
    Score: 0.007
  49. Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure. J Appl Physiol (1985). 1993 Oct; 75(4):1748-57.
    View in: PubMed
    Score: 0.006
  50. Chronic hypoxic pulmonary hypertension. Is thrombin involved? Am Rev Respir Dis. 1993 Oct; 148(4 Pt 1):1043-8.
    View in: PubMed
    Score: 0.006
  51. Postischemic oxygen radical production varies with duration of ischemia. Am J Physiol. 1993 May; 264(5 Pt 2):H1478-84.
    View in: PubMed
    Score: 0.006
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.