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Tong-Chuan He to Signal Transduction

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This is a "connection" page, showing publications Tong-Chuan He has written about Signal Transduction.
Tong-Chuan He
Connection Strength
3.482
Signal Transduction
  1. Monensin inhibits cell proliferation and tumor growth of chemo-resistant pancreatic cancer cells by targeting the EGFR signaling pathway. Sci Rep. 2018 12 17; 8(1):17914.
    View in: PubMed
    Score: 0.316
  2. Modulation of ß-catenin signaling by the inhibitors of MAP kinase, tyrosine kinase, and PI3-kinase pathways. Int J Med Sci. 2013; 10(13):1888-98.
    View in: PubMed
    Score: 0.223
  3. Tetrandrine inhibits Wnt/ß-catenin signaling and suppresses tumor growth of human colorectal cancer. Mol Pharmacol. 2011 Feb; 79(2):211-9.
    View in: PubMed
    Score: 0.180
  4. Activation of RXR and RAR signaling promotes myogenic differentiation of myoblastic C2C12 cells. Differentiation. 2009 Nov; 78(4):195-204.
    View in: PubMed
    Score: 0.164
  5. BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/beta-catenin signalling. J Cell Mol Med. 2009 Aug; 13(8B):2448-2464.
    View in: PubMed
    Score: 0.157
  6. Wnt signaling and human diseases: what are the therapeutic implications? Lab Invest. 2007 Feb; 87(2):97-103.
    View in: PubMed
    Score: 0.138
  7. Wnt/beta-catenin signaling pathway as a novel cancer drug target. Curr Cancer Drug Targets. 2004 Dec; 4(8):653-71.
    View in: PubMed
    Score: 0.120
  8. Transcriptional characterization of bone morphogenetic proteins (BMPs)-mediated osteogenic signaling. J Cell Biochem. 2003 Dec 15; 90(6):1149-65.
    View in: PubMed
    Score: 0.112
  9. Tyrosine kinase inhibitor STI-571/Gleevec down-regulates the beta-catenin signaling activity. Cancer Lett. 2003 Apr 25; 193(2):161-70.
    View in: PubMed
    Score: 0.107
  10. Antiparasitic mebendazole (MBZ) effectively overcomes cisplatin resistance in human ovarian cancer cells by inhibiting multiple cancer-associated signaling pathways. Aging (Albany NY). 2021 07 07; 13(13):17407-17427.
    View in: PubMed
    Score: 0.094
  11. Leptin Potentiates BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells Through the Activation of JAK/STAT Signaling. Stem Cells Dev. 2020 04 15; 29(8):498-510.
    View in: PubMed
    Score: 0.086
  12. Long non-coding RNA (lncRNA) H19 induces hepatic steatosis through activating MLXIPL and mTORC1 networks in hepatocytes. J Cell Mol Med. 2020 01; 24(2):1399-1412.
    View in: PubMed
    Score: 0.085
  13. Imiquimod Acts Synergistically with BMP9 through the Notch Pathway as an Osteoinductive Agent In Vitro. Plast Reconstr Surg. 2019 11; 144(5):1094-1103.
    View in: PubMed
    Score: 0.084
  14. A simplified 3D liver microsphere tissue culture model for hepatic cell signaling and drug-induced hepatotoxicity studies. Int J Mol Med. 2019 Nov; 44(5):1653-1666.
    View in: PubMed
    Score: 0.083
  15. BMP9-induced osteoblastic differentiation requires functional Notch signaling in mesenchymal stem cells. Lab Invest. 2019 01; 99(1):58-71.
    View in: PubMed
    Score: 0.078
  16. Notch Signaling Augments BMP9-Induced Bone Formation by Promoting the Osteogenesis-Angiogenesis Coupling Process in Mesenchymal Stem Cells (MSCs). Cell Physiol Biochem. 2017; 41(5):1905-1923.
    View in: PubMed
    Score: 0.070
  17. Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid's anti-metastatic effect in 4T1 tumor bearing mice. Oncotarget. 2016 Nov 01; 7(44):71802-71816.
    View in: PubMed
    Score: 0.068
  18. Hedgehog signaling is involved in the BMP9-induced osteogenic differentiation of mesenchymal stem cells. Int J Mol Med. 2015 Jun; 35(6):1641-50.
    View in: PubMed
    Score: 0.061
  19. The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways. Curr Cancer Drug Targets. 2015; 15(8):726-38.
    View in: PubMed
    Score: 0.060
  20. TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol. J Pharmacol Sci. 2015 Jan; 127(1):83-91.
    View in: PubMed
    Score: 0.060
  21. Signal transduction in the erythropoietin receptor system. Stem Cells. 1993 Sep; 11(5):381-92.
    View in: PubMed
    Score: 0.055
  22. Inhibition of histone deacetylases potentiates BMP9-induced osteogenic signaling in mouse mesenchymal stem cells. Cell Physiol Biochem. 2013; 32(2):486-98.
    View in: PubMed
    Score: 0.055
  23. Cross-talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells. J Cell Mol Med. 2013 Sep; 17(9):1160-72.
    View in: PubMed
    Score: 0.054
  24. Ginseng saponin metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting multiple cancer signaling pathways. Oncol Rep. 2013 Jul; 30(1):292-8.
    View in: PubMed
    Score: 0.054
  25. Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells. J Bone Miner Res. 2012 Jul; 27(7):1566-75.
    View in: PubMed
    Score: 0.051
  26. Enhancement of canonical Wnt/ß-catenin signaling activity by HCV core protein promotes cell growth of hepatocellular carcinoma cells. PLoS One. 2011; 6(11):e27496.
    View in: PubMed
    Score: 0.048
  27. BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential. Curr Gene Ther. 2011 Jun; 11(3):229-40.
    View in: PubMed
    Score: 0.047
  28. The therapeutic potential of the Wnt signaling pathway in bone disorders. Curr Mol Pharmacol. 2011 Jan; 4(1):14-25.
    View in: PubMed
    Score: 0.046
  29. Ginsenoside Rg3 inhibits colorectal tumor growth through the down-regulation of Wnt/ß-catenin signaling. Int J Oncol. 2011 Feb; 38(2):437-45.
    View in: PubMed
    Score: 0.045
  30. Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov; 29(10):1569-81.
    View in: PubMed
    Score: 0.042
  31. Expression of the Arf tumor suppressor gene is controlled by Tgfbeta2 during development. Development. 2009 Jun; 136(12):2081-9.
    View in: PubMed
    Score: 0.041
  32. Neurogenesis-related genes expression profiling of mouse fibroblastic stem cells induced by Wnt signaling. Neurol Res. 2009 Mar; 31(2):200-3.
    View in: PubMed
    Score: 0.040
  33. Osteosarcoma development and stem cell differentiation. Clin Orthop Relat Res. 2008 Sep; 466(9):2114-30.
    View in: PubMed
    Score: 0.038
  34. Regulation of osteogenic differentiation during skeletal development. Front Biosci. 2008 Jan 01; 13:2001-21.
    View in: PubMed
    Score: 0.037
  35. Distinct roles of bone morphogenetic proteins in osteogenic differentiation of mesenchymal stem cells. J Orthop Res. 2007 May; 25(5):665-77.
    View in: PubMed
    Score: 0.035
  36. CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells. Mol Cell Biol. 2006 Apr; 26(8):2955-64.
    View in: PubMed
    Score: 0.033
  37. Connective tissue growth factor (CTGF) is regulated by Wnt and bone morphogenetic proteins signaling in osteoblast differentiation of mesenchymal stem cells. J Biol Chem. 2004 Dec 31; 279(53):55958-68.
    View in: PubMed
    Score: 0.030
  38. Effect of antibiotic monensin on cell proliferation and IGF1R signaling pathway in human colorectal cancer cells. Ann Med. 2023 12; 55(1):954-964.
    View in: PubMed
    Score: 0.028
  39. Systematic Review of Nonsyndromic Craniosynostosis: Genomic Alterations and Impacted Signaling Pathways. Plast Reconstr Surg. 2024 02 01; 153(2):383e-396e.
    View in: PubMed
    Score: 0.027
  40. Bone morphogenetic protein 4 (BMP4) alleviates hepatic steatosis by increasing hepatic lipid turnover and inhibiting the mTORC1 signaling axis in hepatocytes. Aging (Albany NY). 2019 12 12; 11(23):11520-11540.
    View in: PubMed
    Score: 0.021
  41. ARRB1-Promoted NOTCH1 Degradation Is Suppressed by OncomiR miR-223 in T-cell Acute Lymphoblastic Leukemia. Cancer Res. 2020 03 01; 80(5):988-998.
    View in: PubMed
    Score: 0.021
  42. The cerebral cavernous malformation disease causing gene KRIT1 participates in intestinal epithelial barrier maintenance and regulation. FASEB J. 2019 02; 33(2):2132-2143.
    View in: PubMed
    Score: 0.019
  43. Identification of c-MYC as a target of the APC pathway. Science. 1998 Sep 04; 281(5382):1509-12.
    View in: PubMed
    Score: 0.019
  44. Whole-Proteome Analysis of Human Craniosynostotic Tissue Suggests a Link between Inflammatory Signaling and Osteoclast Activation in Human Cranial Suture Patency. Plast Reconstr Surg. 2018 02; 141(2):250e-260e.
    View in: PubMed
    Score: 0.019
  45. Inhibitory effects of BMP9 on breast cancer cells by regulating their interaction with pre-adipocytes/adipocytes. Oncotarget. 2017 May 30; 8(22):35890-35901.
    View in: PubMed
    Score: 0.018
  46. A Blockade of IGF Signaling Sensitizes Human Ovarian Cancer Cells to the Anthelmintic Niclosamide-Induced Anti-Proliferative and Anticancer Activities. Cell Physiol Biochem. 2016; 39(3):871-88.
    View in: PubMed
    Score: 0.017
  47. Antibiotic monensin synergizes with EGFR inhibitors and oxaliplatin to suppress the proliferation of human ovarian cancer cells. Sci Rep. 2015 Dec 07; 5:17523.
    View in: PubMed
    Score: 0.016
  48. Activation of PKA/CREB Signaling is Involved in BMP9-Induced Osteogenic Differentiation of Mesenchymal Stem Cells. Cell Physiol Biochem. 2015; 37(2):548-62.
    View in: PubMed
    Score: 0.015
  49. Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs). Biomaterials. 2015 Jan; 39:145-54.
    View in: PubMed
    Score: 0.015
  50. BMP9 regulates cross-talk between breast cancer cells and bone marrow-derived mesenchymal stem cells. Cell Oncol (Dordr). 2014 Oct; 37(5):363-75.
    View in: PubMed
    Score: 0.015
  51. Inhibition of erythropoietin-induced mitogenesis by a kinase-deficient form of Jak2. J Biol Chem. 1994 Aug 26; 269(34):21411-4.
    View in: PubMed
    Score: 0.015
  52. Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells. J Orthop Res. 2013 Nov; 31(11):1796-803.
    View in: PubMed
    Score: 0.014
  53. Paraptosis and NF-?B activation are associated with protopanaxadiol-induced cancer chemoprevention. BMC Complement Altern Med. 2013 Jan 03; 13:2.
    View in: PubMed
    Score: 0.013
  54. BMP9-regulated angiogenic signaling plays an important role in the osteogenic differentiation of mesenchymal progenitor cells. J Cell Sci. 2013 Jan 15; 126(Pt 2):532-41.
    View in: PubMed
    Score: 0.013
  55. LIGHT delivery to tumors by mesenchymal stem cells mobilizes an effective antitumor immune response. Cancer Res. 2012 Jun 15; 72(12):2980-9.
    View in: PubMed
    Score: 0.012
  56. All-trans retinoic acid inhibits tumor growth of human osteosarcoma by activating Smad signaling-induced osteogenic differentiation. Int J Oncol. 2012 Jul; 41(1):153-60.
    View in: PubMed
    Score: 0.012
  57. Ginsenoside Rh2 induces apoptosis and paraptosis-like cell death in colorectal cancer cells through activation of p53. Cancer Lett. 2011 Feb 28; 301(2):185-92.
    View in: PubMed
    Score: 0.011
  58. Insulin-like growth factor 2 (IGF-2) potentiates BMP-9-induced osteogenic differentiation and bone formation. J Bone Miner Res. 2010 Nov; 25(11):2447-59.
    View in: PubMed
    Score: 0.011
  59. The CCN proteins: important signaling mediators in stem cell differentiation and tumorigenesis. Histol Histopathol. 2010 06; 25(6):795-806.
    View in: PubMed
    Score: 0.011
  60. Pre-activation of retinoid signaling facilitates neuronal differentiation of mesenchymal stem cells. Dev Growth Differ. 2010 Jun; 52(5):419-31.
    View in: PubMed
    Score: 0.011
  61. Crosstalk between NF-kappaB and beta-catenin pathways in bacterial-colonized intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2005 Jul; 289(1):G129-37.
    View in: PubMed
    Score: 0.008
  62. CDX2 is mutated in a colorectal cancer with normal APC/beta-catenin signaling. Oncogene. 1999 Sep 02; 18(35):5010-4.
    View in: PubMed
    Score: 0.005
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.