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Nike Bharucha

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InstitutionUniversity of Chicago
AddressChicago IL 60637
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liu L, Wu D, Manhas A, Noishiki C, Tripathi D, Sadat S, Bharucha N, Karakikes I, Sallam K, Sayed N. Generation of two homozygous iPSC lines carrying variants of uncertain significance in LMNA associated with cardiomyopathy. Stem Cell Res. 2026 Sep; 95:104086. PMID: 42648117.
      Citations:    
    2. Sainz AG, Kwak CS, Cho KB, Sripadanna SA, Bergsneider BH, Zizzo Z, Durairaj AS, Du Z, Cooney I, Venida A, Bharucha N, Karakikes I, Chiu W, Lim M, Bassik MC, Wang X. The MIRO1-BAX Complex Dictates Life and Death at the Mitochondrial Gate. bioRxiv. 2026 Jun 30. PMID: 42427686; PMCID: PMC13345101.
      Citations:    
    3. Baum R, Telugu N, Bruyneel AAN, Kay M, Nair P, Perea-Gil I, Termglinchan V, Bharucha N, Lee E, Mercola M, Diecke S, Karakikes I. CRISPR-MiX: A pooled single-stranded donor strategy to enhance HDR efficiency in human iPSCs. Mol Ther Nucleic Acids. 2026 Mar 12; 37(1):102820. PMID: 41674724; PMCID: PMC12887267.
      Citations:    
    4. Kay M, Samuelsson AM, Bharucha N, Li X, Ramchandani R, Baum RE, Ruiz Arvizo D, Laguerre A, Lajevardi S, Kambhampati S, Metallo CM, Kapiloff MS, Karakikes I. Enhancing cardiac serine biosynthesis mitigates the progression of dilated cardiomyopathy in mice. Metabolism. 2026 01; 174:156395. PMID: 40975489; PMCID: PMC12885113.
      Citations: 1     Fields:    Translation:AnimalsCells
    5. Ramchandani R, Bharucha N, Karakikes I. Precision unleashed: tackling DNA mismatch repair for enhanced prime editing. Mol Ther Nucleic Acids. 2023 Dec 12; 34:102061. PMID: 38053563; PMCID: PMC10694762.
      Citations:    
    6. Anderson CD, Arthur JA, Zhang Y, Bharucha N, Karakikes I, Shohet RV. Non-viral in vivo cytidine base editing in hepatocytes using focused ultrasound targeted microbubbles. Mol Ther Nucleic Acids. 2023 Sep 12; 33:733-737. PMID: 37662969; PMCID: PMC10468349.
      Citations: 5     
    7. Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M, Karakikes I. Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. Eur Heart J. 2022 09 21; 43(36):3477-3489. PMID: 35728000; PMCID: PMC9794189.
      Citations: 36     Fields:    Translation:HumansCells
    8. Bharucha N, Arias A, Karakikes I. The potential of CRISPR-Cas9 prime editing for cardiovascular disease research and therapy. Curr Opin Cardiol. 2022 09 01; 37(5):413-418. PMID: 35880456; PMCID: PMC10165891.
      Citations: 1     Fields:    Translation:Humans
    9. Metzl-Raz E, Bharucha N, Arthur Ataam J, Gavidia AA, Greenleaf WJ, Karakikes I. Generation of a dual edited human induced pluripotent stem cell Myl7-GFP reporter line with inducible CRISPRi/dCas9. Stem Cell Res. 2022 05; 61:102754. PMID: 35325819; PMCID: PMC9169598.
      Citations:    Fields:    Translation:HumansCells
    10. Bharucha N, Ataam JA, Gavidia AA, Karakikes I. Generation of AAVS1 integrated doxycycline-inducible CRISPR-Prime Editor human induced pluripotent stem cell line. Stem Cell Res. 2021 Dec; 57:102610. PMID: 34875545; PMCID: PMC9126997.
      Citations: 5     Fields:    
    11. Bharucha N, Liu Y, Papanikou E, McMahon C, Esaki M, Jeffrey PD, Hughson FM, Glick BS. Sec16 influences transitional ER sites by regulating rather than organizing COPII. Mol Biol Cell. 2013 Nov; 24(21):3406-19. PMID: 24006484; PMCID: PMC3814151.
      Citations: 40     Fields:    Translation:AnimalsCells
    12. Bharucha N, Chabrier-Rosello Y, Xu T, Johnson C, Sobczynski S, Song Q, Dobry CJ, Eckwahl MJ, Anderson CP, Benjamin AJ, Kumar A, Krysan DJ. A large-scale complex haploinsufficiency-based genetic interaction screen in Candida albicans: analysis of the RAM network during morphogenesis. PLoS Genet. 2011 Apr; 7(4):e1002058. PMID: 22103005; PMCID: PMC3084211.
      Citations: 39     Fields:    Translation:AnimalsCells
    13. Geda P, Patury S, Ma J, Bharucha N, Dobry CJ, Lawson SK, Gestwicki JE, Kumar A. A small molecule-directed approach to control protein localization and function. Yeast. 2008 Aug; 25(8):577-94. PMID: 18668531.
      Citations: 22     Fields:    Translation:AnimalsCells
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