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An epistatic ratchet constrains the direction of glucocorticoid receptor evolution.
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An epistatic ratchet constrains the direction of glucocorticoid receptor evolution.
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution. Nature. 2009 Sep 24; 461(7263):515-9.
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PubMed
subject areas
Animals
CHO Cells
Cricetinae
Cricetulus
Crystallography, X-Ray
Epistasis, Genetic
Evolution, Molecular
Hormones
Models, Biological
Models, Molecular
Mutation
Protein Engineering
Receptors, Glucocorticoid
Sequence Alignment
Substrate Specificity
authors with profiles
Joseph Thornton