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A single-molecule platform for investigation of interactions between G-quadruplexes and small-molecule ligands.
Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester
A large collapsed-state RNA can exhibit simple exponential single-molecule dynamics.
Loose Anagen Hair Syndrome
Click chemistry assisted single-molecule fingerprinting reveals a 3D biomolecular folding funnel.
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Click chemistry assisted single-molecule fingerprinting reveals a 3D biomolecular folding funnel.
Click chemistry assisted single-molecule fingerprinting reveals a 3D biomolecular folding funnel. J Am Chem Soc. 2012 Aug 01; 134(30):12338-41.
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subject areas
Click Chemistry
DNA
G-Quadruplexes
Humans
Kinetics
Models, Molecular
Optical Tweezers
Thermodynamics