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First-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors.
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First-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors.
First-in-human phase I study of Lurbinectedin (PM01183) in patients with advanced solid tumors. Clin Cancer Res. 2014 Apr 15; 20(8):2205-14.
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PubMed
subject areas
Adult
Aged
Anemia
Area Under Curve
Carbolines
Dose-Response Relationship, Drug
Drug Administration Schedule
Fatigue
Female
Heterocyclic Compounds, 4 or More Rings
Humans
Infusions, Intravenous
Male
Metabolic Clearance Rate
Middle Aged
Nausea
Neoplasms
Treatment Outcome
Vomiting
Young Adult
authors with profiles
Mark J. Ratain